Developing a practical resource to improve the ethical standing of gene therapy trials

By Rosie Munday, Hugh Davies and Stephanie Jones with Oxford “A” Health Research Authority Research Ethics Committee Oxford “A” NHS REC is one of the four UK Research Ethics Committees flagged to review gene therapy proposals. Following the philosopher Mary Warnock’s sage advice “I do not believe you can make moral judgements unless, as far […]

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Is the “serious” factor in germline modification really relevant? A response to Kleiderman, Ravitsky and Knoppers

By Iñigo de Miguel Beriain Is the “serious” factor in germline modification relevant? This seems a relevant question in the germline gene editing debate. Of course, at first glance, one tends to choose an affirmative answer immediately. It seems common sense to think that sophisticated technology should be used only when we are faced with […]

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He Jiankui’s Genetic Misadventure: Why Him? Why China?

By Jing-Bao Nie This post first appeared on The Hastings Center Forum on 5 December, 2018. The birth of gene-edited twin girls was announced by a young Chinese scientist He Jiankui through one of four self-made promotional videos in English on YouTube (a website officially banned in China) on November 25. Three days later, at the Second […]

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Rogue scientist: the human CRISPR experiment

By Jeanne Snelling and Mike King Chinese researcher, He Jiankui, claims to have implanted CRISPR-cas9 gene-edited embryos into potentially six women resulting in at least one successful pregnancy (of twins). Given the unconventional and inadequate way information has been released by He, and the fact that the research has not had thorough oversight, the facts […]

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Claims over human genome editing: scientific irresponsibility at its worst

By Sarah Chan This post first appeared in The Motley Coat on 26 November 2018. The announcement made today, that the world’s first genome-edited babies have been born in China, is of grave ethical concern. In evaluating this news, we should first remember that these claims have not yet been scientifically validated through peer reviewed publication […]

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