Even patients with well-controlled disease can have high levels of fear

The FAIR questionnaire could be useful both in routine doctor visits and clinical trials to identify a person’s fear levels about their disease and its treatment INTRODUCTION Rheumatoid arthritis is a chronic (long-term) inflammatory disease that affects a person’s joints, causing pain and disability. It can also affect internal organs. Rheumatoid arthritis is more common […]

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Lymphoma risk in RA is more dependent on the underlying disease than use of bDMARD treatments

There is no evidence that using bDMARDS to treat rheumatoid arthritis has an effect on the type of lymphoma that people might get INTRODUCTION Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, causing pain and disability. It can also affect internal organs. Rheumatoid arthritis affects women more frequently than men. Lymphoma […]

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Using the pill protects women from developing rheumatoid arthritis

Reproductive hormones may play a role in disease development in rheumatoid arthritis. INTRODUCTION Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, causing pain and disability. It can also affect internal organs. Rheumatoid arthritis affects people of all ages, including young adults, adolescents and children, and it affects women more frequently than […]

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Low-dose glucocorticoids are safe to use in early rheumatoid arthritis

This 7-year analysis supports the good safety profile of low-dose glucocorticoids for early active rheumatoid arthritis Introduction Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, causing pain and disability. It can also affect internal organs. Rheumatoid arthritis is more common in older people, but there is also a high prevalence in […]

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ABP501 is equivalent to originator adalimumab

ABP501 is similar to originator adalimumab in clinical efficacy, safety, and immunogenicity INTRODUCTION Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, causing pain and disability. It can also affect internal organs. Rheumatoid arthritis is more common in older people, but there is also a high prevalence in young adults, adolescents and […]

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Moderate alcohol consumption may not affect liver blood tests in people taking methotrexate

Weekly alcohol consumption of less than 14 units per week does not appear to be associated with an increased risk of abnormal liver blood tests. Introduction Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, causing pain and disability. It can also affect internal organs. Rheumatoid arthritis is more common in older […]

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Sticking to a healthy diet over many years may protect against rheumatoid arthritis

Women with a healthy diet may be less likely to develop rheumatoid arthritis Introduction Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, causing pain and disability. It can also affect internal organs. Rheumatoid arthritis is more common in older people, but there is also a high prevalence in young adults, adolescents […]

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No new safety signals with long-term use of tofacitinib

Side effects with tofacitinib are generally stable over time and there are no new safety signals with long-term use INTRODUCTION Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, causing pain and disability. It can also affect internal organs. Rheumatoid arthritis is more common in older people, but there is also a […]

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Short-term changes on MRI predict long-term changes on X-ray

Short-term changes on MRI predict long-term changes on X-ray MRI is a valid method for monitoring joint damage in short-duration randomised clinical trials. INTRODUCTION Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, causing pain and disability. Although many treatments that stop inflammation and joint destruction have been introduced over the past […]

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Filgotinib is effective in people with insufficient response to methotrexate

Filgotinib improved signs and symptoms of rheumatoid arthritis over 24 weeks and was associated with fast onset of action. INTRODUCTION Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, causing pain and disability. Filgotinib belongs to a new group of medicines called targeted synthetic disease modifying antirheumatic drugs (sometimes also called tsDMARDs). […]

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