Increased COVID-19 risk in autoimmune disease, but not more severe

People with autoimmune disease have an increased risk of getting infected with COVID-19, especially if they use steroid medicines. However, the risk of severe outcomes of COVID-19 such as hospitalisation or death is not increased. INTRODUCTION COVID-19 is the disease caused by a new type of coronavirus called severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). It […]

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Managing lupus nephritis

This is the lay version of the 2019 update of the EULAR recommendations for the management of people with lupus nephritis. The original publication can be downloaded from the EULAR website: www.eular.org. Fanouriakis A, et al. 2019 Update of the Joint European League Against Rheumatism and European Renal Association–European Dialysis and Transplant Association (EULAR/ERA–EDTA) recommendations […]

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Blocking interferon results in clinical improvement for people with lupus

The type I interferon pathway contributes to the development of lupus. INTRODUCTION Systemic lupus erythematosus (also known as SLE or lupus) is an autoimmune disease. It typically affects women between the ages of 15 and 50, and symptoms flare up unpredictably. Lupus is caused by complicated interactions between the immune system and environmental factors leading […]

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Potential treatment for lupus nephritis without oral steroids

INTRODUCTION A small study of a new combination treatment for lupus nephritis that doesn’t include oral steroids has shown encouraging results. If larger studies show similar results, the new combination treatment could help people with this condition avoid the side effects of long-term treatment with high doses of oral steroids. WHAT DO WE KNOW ALREADY? Lupus nephritis […]

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