Higher inflammatory burden than previously anticipated

Axial inflammation seen in people with early peripheral spondyloarthritis, but not predictive of relapse in those achieving remission. INTRODUCTION Spondyloarthritis (shortened to SpA) refers to a spectrum of related rheumatic diseases caused by chronic inflammation. Many people with spondyloarthritis also have non-joint symptoms, such as psoriasis of the skin and nails, inflammatory bowel disease and […]

Read More…

IL-17- or TNF inhibitors have comparable efficacy after failure of previous TNF inhibitors

Symptom relief and time on therapy are similar for people taking TNF inhibitors or secukinumab after previous TNF inhibitor failure. INTRODUCTION Spondyloarthritis (often shortened to SpA) is an umbrella term for several conditions that share many features and symptoms. These conditions include ankylosing spondylitis, psoriatic arthritis and reactive arthritis. Spondyloarthritis can be classified as axial […]

Read More…

Work is more affected for people in rural areas

Geography plays a role in health and work outcomes. INTRODUCTION Spondyloarthritis (often shortened to SpA) is an umbrella term for several conditions that share many features and symptoms. These conditions include ankylosing spondylitis, psoriatic arthritis and reactive arthritis. Spondyloarthritis can be classified as axial or non-axial (peripheral), according to which regions in the body are […]

Read More…

Individual- and country-level health inequalities exist in people with SpA

After taking other factors into account, women and people with lower levels of education have worse disease activity. Introduction Spondyloarthritis (often shortened to SpA) is an umbrella term for several conditions that share many features and symptoms. Thesec onditions include ankylosing spondylitis, psoriatic arthritis and reactive arthritis. Spondyloarthritis can be classified as axial or non […]

Read More…

Managing axial spondyloarthritis

This is the lay version of the EULAR recommendations for the management of people with axial spondyloarthritis. The original publication can be downloaded from the EULAR website: www.eular.org. van der Heijde D, et al. 2016 update of the ASAS-EULAR management recommendations for axial spondyloarthritis. Ann Rheum Dis 2017;76:978–991. doi:10.1136/annrheumdis-2016-210770 Introduction  EULAR recommendations give advice to […]

Read More…

Even patients with well-controlled disease can have high levels of fear

The FAIR questionnaire could be useful both in routine doctor visits and clinical trials to identify a person’s fear levels about their disease and its treatment INTRODUCTION Rheumatoid arthritis is a chronic (long-term) inflammatory disease that affects a person’s joints, causing pain and disability. It can also affect internal organs. Rheumatoid arthritis is more common […]

Read More…

Possible new onset or worsening of sacroiliitis or arthritis in people taking vedolizumab for IBD

Possible new onset or worsening of sacroiliitis or arthritis in people taking vedolizumab for IBD Vedolizumab might induce arthritis or sacroiliitis in people with IBD INTRODUCTION Inflammatory bowel disease (often shortened to IBD) is a long-term condition that affects a person’s digestive tract. IBD includes two conditions: ulcerative colitis and Crohn’s disease, which share many […]

Read More…

Disease activity and inflammation is linked to spinal damage, even in early disease

Disease activity is associated with radiographic spinal progression in early axial spondyloarthritis. INTRODUCTION Ankylosing spondylitis is a chronic inflammatory disease. It mainly involves the spine, but may be associated with other diseases, such as psoriasis (a skin disease), inflammatory bowel disease and uveitis (an inflammation in the eye). These non-joint symptoms are known as extra-articular […]

Read More…

A step closer to defining ‘flare’ in people with axial spondyloarthritis

Flares may be used as outcomes in trials and studies, but to date there is no agreed consensus on how to define them in people with axial spondyloarthritis. INTRODUCTION Spondyloarthritis is an umbrella term for several conditions that share many of the same features and symptoms, including ankylosing spondylitis, psoriatic arthritis and reactive arthritis. Patients […]

Read More…

Smoking can reduce the efficacy of medicines for axial spondyloarthritis

Smoking may interfere with how biologic medicines reduce inflammation and joint damage in people with axial spondyloarthritis. INTRODUCTION Spondyloarthritis is an umbrella term for several conditions that share many of the same features and symptoms, including ankylosing spondylitis, psoriatic arthritis and reactive arthritis. Patients can also be classified as having axial or non-axial (peripheral) disease, […]

Read More…