Disease activity and inflammation is linked to spinal damage, even in early disease

Disease activity is associated with radiographic spinal progression in early axial spondyloarthritis. INTRODUCTION Ankylosing spondylitis is a chronic inflammatory disease. It mainly involves the spine, but may be associated with other diseases, such as psoriasis (a skin disease), inflammatory bowel disease and uveitis (an inflammation in the eye). These non-joint symptoms are known as extra-articular […]

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A step closer to defining ‘flare’ in people with axial spondyloarthritis

Flares may be used as outcomes in trials and studies, but to date there is no agreed consensus on how to define them in people with axial spondyloarthritis. INTRODUCTION Spondyloarthritis is an umbrella term for several conditions that share many of the same features and symptoms, including ankylosing spondylitis, psoriatic arthritis and reactive arthritis. Patients […]

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Smoking can reduce the efficacy of medicines for axial spondyloarthritis

Smoking may interfere with how biologic medicines reduce inflammation and joint damage in people with axial spondyloarthritis. INTRODUCTION Spondyloarthritis is an umbrella term for several conditions that share many of the same features and symptoms, including ankylosing spondylitis, psoriatic arthritis and reactive arthritis. Patients can also be classified as having axial or non-axial (peripheral) disease, […]

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EULAR recommendations for the use of imaging in spondyloarthritis

Imaging techniques are a key component of the classification of spondyloarthritis, allowing patients to be classi- fied into distinct groups and to receive the appropriate treatment. INTRODUCTION Spondyloarthritis is an umbrella term for several conditions that share many of the same features and symptoms, including ankylosing spondylitis, psoriatic arthritis and reactive arthritis. Patients can also […]

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Why anti-TNF treatments don’t work the same for everyone

  INTRODUCTION Some people who take treatments called anti-TNF drugs for illnesses like rheumatoid arthritis, psoriasis and spondyloarthritides may get less benefit than other people who take the same treatments, because their immune systems stop the drugs working properly. WHAT DO WE KNOW ALREADY? Anti-TNF drugs are used to reduce inflammation (for example joint swelling). […]

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