In newly diagnosed people undergoing rapid glucocorticoid tapering, tocilizumab was superior to placebo INTRODUCTION Polymyalgia rheumatica (shortened to PMR) is the second most common inflammatory rheumatic disease in people over the age of 50. Symptoms include pain in the neck, shoulders, and hips, as well as morning stiffness. PMR can be treated with glucocorticoids (also […]
Category: Steroids
Steroid dose and duration linked to cardiovascular events in RA
Dose and duration are associated with an increased risk for incident cardiovascular events in steroid-naïve patients INTRODUCTION Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, and may cause pain and disability. Rheumatoid arthritis can affect people of all ages, but it most often starts between the ages of 30 and 50 […]
Intensive treatments deliver good long-term results
The COBRA-Slim treatment is as effective as more complex treatments for high-risk patients with early RA INTRODUCTION Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, and may cause pain and disability. Rheumatoid arthritis can affect people of all ages, but it most often starts between the ages of 30 and 50 […]
Fracture risk should be considered for people taking oral steroids and PPIs
There is an increased risk of osteoporotic fractures in people using both oral glucocorticoids and proton-pump inhibitors. INTRODUCTION Rheumatoid arthritis is a chronic inflammatory disease that can affect a person’s joints, and may cause pain and disability. Rheumatoid arthritis affects people of all ages, and is more common in women than men. One of the […]
People can regain remission after relapse with rituximab plus steroids
Rituximab plus steroids are useful for putting people back into remission after a relapse of their AAV. INTRODUCTION ANCA-associated vasculitis (shortened to AAV), is a rare group of diseases of the immune system. These diseases are linked to a type of autoantibody called ANCA. An antibody is a protein that the normal healthy immune system […]
Cytokine storm is a treatable complication of COVID-19
Use of an immunosuppressive strategy can improve recovery and lower death rates in COVID-19-associated CSS. INTRODUCTION COVID-19 is the disease caused by a new type of coronavirus called severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). It was declared a pandemic by the World Health Organization on 11 March 2020. COVID-19 has forced people to change their […]
Potential Positive Benefits of Nutritious, Well-balanced Diet in People with Lupus
Cecilia Lourdudoss, Ph.D. student at the Unit for Research Therapy, Inflammatory Diseases (ClinTRID), Karolinska Institutet in Stockholm, Sweden, spoke with the Lupus Foundation of America recently about her latest research findings on the association of diet and steroid use in people with lupus, published in Lupus Science & Medicine. In this study, vitamin D was […]
Joint EULAR and ACR recommendations for best practice in polymyalgia rheumatica
Steroids are the best option for patients with polymyalgia rheumatica. INTRODUCTION Polymyalgia rheumatica is an inflammatory condition that causes pain and stiffness in the muscles, usually around the upper arms, shoulders, neck and hips or thighs. The stiffness is worse in the mornings and can severely limit movement and activities. The cause of polymyalgia rheumatic […]
