Changes may be needed to improve the usefulness of remission definitions

Adapting the thresholds in the Boolean remission definition would improve patient evaluation. Introduction Rheumatoid arthritis is a chronic inflammatory disease that can affect a person’s joints, and may cause pain and disability. Rheumatoid arthritis affects people of all ages, and is more common in women than men. The goal of treatment for rheumatoid arthritis is […]

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T2T in real-life helps people get to remission

Rheumatologists should follow a T2T-strategy in patients with both early and established rheumatoid arthritis. Introduction Rheumatoid arthritis is a chronic inflammatory disease that can affect a person’s joints, and may cause pain and disability. Rheumatoid arthritis affects people of all ages, and is more common in women than men. ‘Treat to target’ (often shortened to […]

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Unclear benefit of Zostavax in people starting on tofacitinib

Zostavax may not provide adequate long-term protection in people taking tofacitinib for their rheumatoid arthritis. Introduction Rheumatoid arthritis is a chronic inflammatory disease that can affect a person’s joints, and may cause pain and disability. Rheumatoid arthritis affects people of all ages, and is more common in women than men. People with rheumatoid arthritis naturally […]

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Success of infliximab discontinuation depends on disease activity at the start of treatment

This tailored treatment strategy did not statistically increase sustained remission after 1 year discontinuation. Introduction Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, causing pain and possible disability. Rheumatoid arthritis affects people of all ages, and is more common in women than men. Treatments for rheumatoid arthritis aim to improve symptoms […]

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Standardisation is needed for sick leave and disability rules for people with RA

There is large variation between countries in Europe in the rules for sick leave and work disability pensions. Introduction Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, causing pain and disability. Rheumatoid arthritis affects people of all ages, although it is more common in women than men. Rheumatoid arthritis can affect […]

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Fracture risk is increased with opioids, SSRIs and glucocorticoids, but decreased with statins and TNFi

Some treatments for rheumatoid arthritis may help lower the risk of spinal fractures. Introduction Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, causing pain and disability. Rheumatoid arthritis is more common in older people, but there is also a high prevalence in young adults and even children, and it affects women […]

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Switch to baricitinib delivers results with no need for washout

Switching from adalimumab to baricitinib delivers improvements in disease control, physical function and pain within 12 weeks, without additional side effects. Introduction Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, causing pain and disability. It can also affect internal organs. Rheumatoid arthritis is more common in older people and it affects […]

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Family link for cardiovascular disease

Rheumatoid arthritis and acute coronary syndrome have a shared association within families. Introduction Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, causing pain and disability. Due to the inflammatory process, also internal organs, especially the heart, may also be affected over time. Rheumatoid arthritis is more common in older than young […]

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Risk of some types of serious bacterial infection are higher with tocilizumab than TNFi

Serious bacterial infection, skin and soft tissue infection, and diverticulitis are more common with tocilizumab than TNFi, but there is no overall difference in the rates of serious infection including bacterial, viral or opportunistic infection. Introduction Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, causing pain and disability. It can also […]

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Disease control can affect quality of life and happiness

The impact of rheumatoid arthritis is less in people with ’positive’ personality traits. Introduction Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, causing pain and disability. It can also affect internal organs. Rheumatoid arthritis is more common in older people, but there is also a high prevalence in young adults, adolescents […]

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