Breakthrough COVID-19 had lower hospitalisation and mortality in vaccinated patients INTRODUCTION COVID-19 is the disease caused by a new type of coronavirus called severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). It was declared a pandemic by the World Health Organization on 11 March 2020. COVID-19 has forced people to change their behaviours to try to limit […]
Category: Rheumatoid arthritis
Comparison of heart attack risk across biologic DMARDs
The risk of acute coronary syndrome varies little across individual bDMARDs in people with rheumatoid arthritis INTRODUCTION Rheumatoid arthritis (shortened to RA) is a chronic inflammatory disease that affects a person’s joints, and may cause pain and disability. RA can affect people of all ages, but the risk increases with age. RA is more common […]
Predicting treatment success in rheumatoid arthritis
Particularly in early disease, prediction can be achieved for people with lower baseline levels of diseases activity INTRODUCTION Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, and may cause pain and disability. Rheumatoid arthritis can affect people of all ages, but it most often starts between the ages of 40 and […]
Over time, joint swelling recurs in the same joints in people with RA
The results suggest that local factors influence joint inflammation over time. INTRODUCTION Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, and may cause pain and disability. Rheumatoid arthritis can affect people of all ages, but it most often starts between the ages of 40 and 50 – although this can depend […]
Steroid dose and duration linked to cardiovascular events in RA
Dose and duration are associated with an increased risk for incident cardiovascular events in steroid-naïve patients INTRODUCTION Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, and may cause pain and disability. Rheumatoid arthritis can affect people of all ages, but it most often starts between the ages of 30 and 50 […]
First study to show inflammatory arthritis can affect male fertility
Men diagnosed with inflammatory arthritis before and during the peak of reproductive age have lower fertility. INTRODUCTION Inflammatory arthritis is a group of diseases including spondyloarthritis, rheumatoid arthritis, and psoriatic arthritis. These are chronic inflammatory diseases that affects a person’s joints, and may cause pain and disability. Inflammatory arthritis can affect people before or during […]
Methotrexate associated with reduced risk of cardiovascular disease in RA
Methotrexate-related mechanisms may modify cardiovascular risk in people with rheumatoid arthritis. INTRODUCTION Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, and may cause pain and disability. Rheumatoid arthritis can affect people of all ages. It most often starts between the ages of 30 and 50 – although this can depend on […]
Medication use for rheumatoid arthritis affects COVID-19 outcomes
People with rheumatoid arthritis treated with rituximab or JAKi have worse COVID-19 severity than those on TNFi INTRODUCTION COVID-19 is the disease caused by a new type of coronavirus called severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). It was declared a pandemic by the World Health Organization on 11 March 2020. COVID-19 has forced people to […]
For COVID-19, general health status matters more than inflammatory arthritis
For people with inflammatory arthritis, overall COVID-19 risks are low and similar to those in the general population. INTRODUCTION COVID-19 is the disease caused by a new type of coronavirus called severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). It was declared a pandemic by the World Health Organization on 11 March 2020. COVID-19 has forced people […]
Intensive treatments deliver good long-term results
The COBRA-Slim treatment is as effective as more complex treatments for high-risk patients with early RA INTRODUCTION Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, and may cause pain and disability. Rheumatoid arthritis can affect people of all ages, but it most often starts between the ages of 30 and 50 […]
