On “clinical vulnerability” during COVID-19

Blog entry written on: ‘Asthma and COVID-19: a review of evidence on risks and management considerations’ (bmjebm-2020-111506) Authors: Jamie Hartmann-Boyce, James Gunnell, Jonny Drake, Afolarin Otunla, Jana Suklan, Ella Schofield, Jade Kinton, Matt Inada-Kim, F D Richard Hobbs, Paddy Dennison Not all reasonable assumptions prove true. At the beginning of the COVID-19 pandemic all people […]

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Tackling incomplete and inadequate reporting of mediation studies

In the process of tackling incomplete and inadequate reporting of mediation studies, Aidan Cashin & Hopin Lee share the findings of their recent publication identifying items for consideration in A Guideline for Reporting Mediation Analysis (AGReMA). Blog entry written on: ‘Items for consideration in a reporting guideline for mediation analyses: a Delphi study’ (bmjebm-2020-111406) Authors: […]

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Caffeine and Pregnancy: Why Current Guidelines Must Change!

This Spotlight Blog relates to the following article in BMJ Evidence-Based Medicine: “Maternal Caffeine Consumption and Pregnancy Outcomes: A Narrative Review with Implications for Advice to Mothers and Mothers-To-Be” (ID No.: bmjebm-2020-111432.R2) Blog entry written on: ‘Maternal Caffeine Consumption and Pregnancy Outcomes: A Narrative Review with Implications for Advice to Mothers and Mothers-To-Be’ (bmjebm-2020-111406), with […]

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Instructions for the day of your surgery: “Please create a playlist of your favourite music”

Blog entry written on: Heterogeneity of Outcomes for Intraoperative Music Interventions: A Scoping Review and Evidence Map (bmjebm-2020-111382) Authors: Melanie Ambler, Stacey Springs, Dioscaris Garcia, Christopher Born We know that 87% of operating room staff report listening to music in the OR, but an emerging body of evidence suggests that listening to music during surgical […]

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Can an antibiotic make you pregnant?

Blog entry written on: Analysis of reports of unintended pregnancies associated with the combined use of non-enzyme-inducing antibiotics and hormonal contraceptives (bmjebm-2020-111363) Authors: Jeffrey K Aronson & Robin E Ferner The British National Formulary (BNF) currently advises women to continue with their usual oral contraception when they start an antibiotic (except for enzyme inducers, e.g. […]

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Honey for coughs and colds: not too shab-bee

Blog entry written on: Effectiveness of honey for symptomatic relief in upper respiratory tract infections: a systematic review and meta-analysis (bmjebm-2020-111336) Author: Hibatullah Abuelgasim Honey is a folklore favourite when it comes to cough and cold remedies. Everyone who has ever had a cold knows how annoying the symptoms can be. Unfortunately, there’s not much […]

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The Dangers of Selective Analysis: Has stroke treatment been misguided for a decade?

  Alteplase is widely recommended for treatment of stroke occurring within 3-4.5 hours. Brian Alper discusses their recent publication that reanalysed the Third European Cooperative Acute Stroke Study (ECASS III) trial through adjustment for baseline imbalances. Blog entry written on: Thrombolysis with alteplase 3–4.5 hours after acute ischaemic stroke: trial reanalysis adjusted for baseline imbalances (bmjebm-2020-111386) […]

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How are you managing hip fracture patients on DOACs?

In an attempt to end the dilemma surrounding the management of hip fracture patients on direct oral anticoagulants, Sheweidin Aziz, Krishan Almeida, and Grahame Taylor share the highlights of their recent publication. Blog entry written on: How should we manage hip fracture patients on direct oral anticoagulants? (bmjebm-2019-111317) Authors: Sheweidin Aziz, Krishnan Almeida, and Grahame […]

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Shining a spotlight on the policies of pain journals

Journals are key stakeholders in the quest for greater transparency and reproducibility of research. Georgia Richards, Aidan Cashin, Matthew Bagg, Elaine Toomey, James McAuley and Hopin Lee discuss their recent publication that evaluates the policies and standards of pain journals. Blog entry written on: Limited engagement with transparent and open science standards in the policies […]

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Should asthma patients increase their steroid inhalers during an attack?

  EBM Practice Spotlight highlights new evidence that challenges current clinical practice Kamal Mahtani Asthma is a long-term condition affecting more than 300 million people (adults and children) worldwide. In the UK, it affects about 1 in every 10 people. When asthma management is effective, patients should be able to continue their normal activities of […]

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