The Dangers of Selective Analysis: Has stroke treatment been misguided for a decade?

  Alteplase is widely recommended for treatment of stroke occurring within 3-4.5 hours. Brian Alper discusses their recent publication that reanalysed the Third European Cooperative Acute Stroke Study (ECASS III) trial through adjustment for baseline imbalances. Blog entry written on: Thrombolysis with alteplase 3–4.5 hours after acute ischaemic stroke: trial reanalysis adjusted for baseline imbalances (bmjebm-2020-111386) […]

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How are you managing hip fracture patients on DOACs?

In an attempt to end the dilemma surrounding the management of hip fracture patients on direct oral anticoagulants, Sheweidin Aziz, Krishan Almeida, and Grahame Taylor share the highlights of their recent publication. Blog entry written on: How should we manage hip fracture patients on direct oral anticoagulants? (bmjebm-2019-111317) Authors: Sheweidin Aziz, Krishnan Almeida, and Grahame […]

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Shining a spotlight on the policies of pain journals

Journals are key stakeholders in the quest for greater transparency and reproducibility of research. Georgia Richards, Aidan Cashin, Matthew Bagg, Elaine Toomey, James McAuley and Hopin Lee discuss their recent publication that evaluates the policies and standards of pain journals. Blog entry written on: Limited engagement with transparent and open science standards in the policies […]

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Should asthma patients increase their steroid inhalers during an attack?

  EBM Practice Spotlight highlights new evidence that challenges current clinical practice Kamal Mahtani Asthma is a long-term condition affecting more than 300 million people (adults and children) worldwide. In the UK, it affects about 1 in every 10 people. When asthma management is effective, patients should be able to continue their normal activities of […]

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