The Dangers of Selective Analysis: Has stroke treatment been misguided for a decade?

  Alteplase is widely recommended for treatment of stroke occurring within 3-4.5 hours. Brian Alper discusses their recent publication that reanalysed the Third European Cooperative Acute Stroke Study (ECASS III) trial through adjustment for baseline imbalances. Blog entry written on: Thrombolysis with alteplase 3–4.5 hours after acute ischaemic stroke: trial reanalysis adjusted for baseline imbalances (bmjebm-2020-111386) […]

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How are you managing hip fracture patients on DOACs?

In an attempt to end the dilemma surrounding the management of hip fracture patients on direct oral anticoagulants, Sheweidin Aziz, Krishan Almeida, and Grahame Taylor share the highlights of their recent publication. Blog entry written on: How should we manage hip fracture patients on direct oral anticoagulants? (bmjebm-2019-111317) Authors: Sheweidin Aziz, Krishnan Almeida, and Grahame […]

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Shining a spotlight on the policies of pain journals

Journals are key stakeholders in the quest for greater transparency and reproducibility of research. Georgia Richards, Aidan Cashin, Matthew Bagg, Elaine Toomey, James McAuley and Hopin Lee discuss their recent publication that evaluates the policies and standards of pain journals. Blog entry written on: Limited engagement with transparent and open science standards in the policies […]

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Clinical Trials transparency is failing – here’s why

  ‘the current system is failing, and awareness isn’t  ‘variable’, it is wholly inappropriate and unethical.’ Carl Heneghan The UK’s House of Commons Science and Technology Committee released its report on clinical trials transparency last week and it makes for a sorry read. Clinical trials transparency means ensuring clinical trials are recorded in a publicly-accessible […]

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BMJ Evidence-Based Medicine Strategy

  BMJ EBM publishes original evidence-based research, insights and opinions on what matters for health care. Carl Heneghan, Editor in Chief, BMJ EBM The BMJ Evidence-Based Medicine strategy focuses on the tools, methods, and concepts that are basic and central to practising evidence-based medicine.     How we deliver relevant, trustworthy and impactful evidence: By Disseminating relevant research: saving […]

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What I learned from Evidence Live 2017: Fixing the “E” in EBM

On the longest (and probably hottest) day of 2017, Evidence Live kicked off at the Blavatnik School of Government, University of Oxford. Professor Carl Heneghan, new Editor-in-Chief of BMJ Evidence-Based Medicine (EBM), opened the conference with the EBM manifesto which recognizes problems in research evidence and proposes actions needed to tackle these problems. This is my summary […]

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