Uncertain about reliably combining randomised and non-randomised studies in healthcare decision-making? Here’s a seven-step framework.

Blog entry written on “A Framework For The Synthesis of Non-Randomized Studies and Randomized Controlled Trials: A Guidance On Conducting A Systematic Review and Meta-analysis For Healthcare Decision-Making” (bmjebm-2020-111493) Authors: Grammati Sarri (Real World Evidence Strategy Lead, Visible Analytics Ltd, UK) and Thomas Debray (Assistant Professor, University Medical Center Utrecht, Utrecht, The Netherlands and Smart […]

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Conflicts of Interest in Medicine: Moving into the Next Decade

Blog entry written on: Ten years later: a review of the US 2009 institute of medicine report on conflicts of interest and solutions for further reform, (bmjebm-2020-111503) Authors: Trevor Torgerson, Cole Wayant, Lisa Cosgrove, Elie A Akl, Jake Checketts, Rafael Dal Re, Jennifer Gill, Samir C Grover, Nasim Khan, Rishad Khan, Ana Marušić, Matthew S […]

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Seeing is believing: blinding practices during point-of-care ultrasound research

Blog entry written on: Blinding practices during acute point-of-care ultrasound research: the BLIND-US meta-research study, (bmjebm-2020-111577) Authors: Ross Prager, Kay Wu2, Roudi Bachar, Rudy R Unni, Joshua Bowdridge, Trevor A McGrath, Rajiv Thavanathan, Michael Y Woo, Matthew D F McInnes Point of care ultrasound (POCUS) has become an invaluable tool for many clinicians. As the […]

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Genetic therapies: still science fiction or now science fact?

“Blog entry written on: An evidence map of randomised controlled trials evaluating genetic therapies, (bmjebm-2020-111448) Authors: Eric A. Apaydin, Andrea S. Richardson, Sangita Baxi, Jerry Vockley, Olamigoke Akinniranye, Rachel Ross, Jody Larkin, Aneesa Motala, Gulrez Azhar, Susanne Hempel. The 1997 sci-fi film Gattaca foretold of a dark future in which parents regularly engaged in eugenics […]

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Methods for teaching EBM: what’s the best bet?

“Blog entry written on: (IV)Integrating evidence-based medicine skills into a medical school curriculum: a quantitative outcomes assessment, (bmjebm-2020-111391). Authors: Laura Menard, Amy E Blevins, Daniel J Trujillo, Kenneth H Lazarus As medical research continues to accelerate, the need for trainees to demonstrate progressive competency of evidence-based medicine (EBM) skills will only continue to grow. Medical […]

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Testing for COVID-19: still many unknowns

Blog entry written on: ‘Effectiveness of tests to detect the presence of SARS-CoV-2 virus, and antibodies to SARS-CoV-2, to inform COVID-19 diagnosis: a rapid systematic review’ (bmjebm-2020-111511). Authors: David Jarrom, Lauren Elston, Jennifer Washington, Matthew Prettyjohns, Kimberley Cann, Susan Myles, Peter Groves. As the COVID-19 pandemic spread at the start of 2020, there was a […]

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Seeing is believing – the problem of blinding in psychological research

Include “Blog entry written on: “Blinding in randomised clinical trials of psychological interventions: a retrospective study of published trial reports” (bmjebm-2020-111407) Authors: Sophie Juul, Christian Gluud, Sebastian Simonsen, Frederik Weischer Frandsen, Irving Kirsch, Janus Christian Jakobsen. Blinding of key persons is rarely reported or implemented in randomised clinical trials of psychological interventions, and only few […]

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How medical training needs to change to allow true evidence-informed decision-making

Blog entry written on: Teaching clinicians shared decision making and risk communication online: an evaluation study (bmjebm-2020-111521) Authors: Alexandra Freeman, Tammy C. Hoffmann, Chris Del Mar, Ramai Santhirapala At the heart of evidence-based medicine is a pipeline: a flow of knowledge and insight from researchers’ computers to the patient’s clinic, where their clinician can explain their […]

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On “clinical vulnerability” during COVID-19

Blog entry written on: ‘Asthma and COVID-19: a review of evidence on risks and management considerations’ (bmjebm-2020-111506) Authors: Jamie Hartmann-Boyce, James Gunnell, Jonny Drake, Afolarin Otunla, Jana Suklan, Ella Schofield, Jade Kinton, Matt Inada-Kim, F D Richard Hobbs, Paddy Dennison Not all reasonable assumptions prove true. At the beginning of the COVID-19 pandemic all people […]

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Tackling incomplete and inadequate reporting of mediation studies

In the process of tackling incomplete and inadequate reporting of mediation studies, Aidan Cashin & Hopin Lee share the findings of their recent publication identifying items for consideration in A Guideline for Reporting Mediation Analysis (AGReMA). Blog entry written on: ‘Items for consideration in a reporting guideline for mediation analyses: a Delphi study’ (bmjebm-2020-111406) Authors: […]

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