Canada’s Federal Court has just rendered a milestone decision for clinical trial transparency. In the case of Peter Doshi v. Attorney General of Canada (yes, that’s one of us), Justice […]
Open data
Richard Smith: A Big Brother future for science publishing?
There have been big changes in science publishing in the 25 years since the appearance of the internet, but at the same time science publishing is still dominated by journals, […]
Kamal R Mahtani, Tom Jefferson, and Carl Heneghan: What makes a systematic review “complex”?
Kamal R Mahtani, Tom Jefferson, and Carl Heneghan reflect on the lack of definitions, and propose a solution […]
Joel Lexchin: Health Canada promises a new era in transparency
In March 2017 Health Canada released a discussion paper promising a new era in transparency. The agency committed itself to proactively releasing clinical trial data submitted by drug companies, similar […]
Simon Denegri: Is a better public debate about patient data on the horizon?
Few would argue that the public have been well served by the debate about how their data can support care and research now and in the future. After the shipwreck […]
Kamal R Mahtani: Using systematic reviews to reduce research waste—who really cares?
The global spend on biomedical research and development is about $250 billion, so why is so much of it still wasted, asks Mahtani […]
Paul Glasziou and Iain Chalmers: Ill informed replications will increase our avoidable waste of research
How does the replicability crisis relate to the estimated 85% waste in medical research? […]
Paul Glasziou: How to hide trial results in plain sight
Paul Glasziou discusses why trial results need to be better presented, so that readers can understand and act on the results. […]
Tom Jefferson: The EMA’s policy 0070 is live
Yesterday the European Medicines Agency’s (EMA’s) long awaited policy 0070 went live. I have previously described the policy, its aims, advantages, possible limitations, and potential impact on everyone here and […]
Chris Simms: The Iraq war, Chilcot, and cherry picking data: How to find a way forward?
The first week of July 2016 was a week to remember. A cluster of war related stories dominated the media, including the 100th anniversary of the Battle of the Somme (1 […]