By Dr Johnny Sakr Genetic testing is often assessed by asking a familiar question: does it change clinical management? If the answer is yes, the value of the test is relatively easy to explain. It may guide treatment, avoid unnecessary investigations, or improve health outcomes. But many genomic tests produce information that families value even […]
Category: Genetic testing
Should we routinely reinterpret genomic results?
By Gabriel Watts and Ainsley J. Newson. Data obtained from genomic sequencing has an interesting quality. Unlike most other kinds of health results, the stored information remains accurate over time, because it reflects a largely stable property of our bodies: our DNA. Of course, during this time, sequencing methods themselves are likely to have advanced […]
Eugenics and reproductive carrier screening: why would you go there?
By Lisa Dive & Ainsley J Newson. It seems that one of the best ways a bioethics academic can attract an avalanche of very strong opinions is to publish a paper with the word “eugenics” in the title. Why then would we do so? In short, because we consider it important to pay attention to […]
Who’s responsible for informing relatives about genetic risk?
By Kalle Grill and Anna Rosén. It is established practice in many countries that healthcare professionals encourage patients to share relevant risk information with genetic relatives. We mostly endorse this practice but question a normative assumption that typically underpins it. Both practitioners and academics in the field are in general agreement that: It is desirable […]
Open future or an informed present? Cancer predispositions testing in children
By Sapna Mehta, Dennis John Kuo. Teenagers, and indeed all children to various extents, live in a world that does not recognize their independence fully. In various situations, they find their rights being exercised by and interests being defined by parents as well as other authorities such as physicians, teachers and the state to a […]
“We think you may be at risk of a genetic disease”. Should direct-to-consumer genetic testing companies contact at-risk relatives?
By Philip E Baker and Jordan A Parsons. Direct-to-consumer (DTC) genetic testing is becoming increasingly popular. However, with genetic testing comes the possibility of discovering mutations that confer increased risk of genetic diseases not only to the tested individual (the proband), but also their genetic relatives. This raises the challenging ethical question of what should […]