Inflammatory mechanisms and organ damage impact cognitive functioning in people with Lupus. Introduction Systemic lupus erythematosus (often called Lupus or SLE) is an autoimmune disease. It typically starts in women between the ages of 15 and 45. Lupus causes immune cells in the body to become hyperactive and produce autoantibodies. An antibody is a protein […]
Category: Systemic lupus erythematosus
New medicines for Lupus should also be tested in children with Lupus
Innovative new trial designs mean it will be possible to test new medicines in rare diseases such as childhood Lupus. Introduction Systemic lupus erythematosus (often called Lupus or SLE) is an autoimmune disease. It typically affects women between the ages of 15 and 45, but can start in younger children. There are many things that […]
Drug-induced lupus is a constantly evolving disease
The list of medicines suspected of causing drug-induced lupus maybe useful to doctors for diagnosis and management of people with this disease. Introduction Systemic lupus erythematosus (often shortened to SLE) is an autoimmune disease. It typically affects women between the ages of 15 and 45. The exact cause of the disease is unknown, but occasionally […]
Women’s health in lupus and APS
This is the lay version of the EULAR recommendations for the management of women’s health and family planning in women with lupus and/or antiphospholipid syndrome. The original publication details the recommendations on use of medications, clinical focus points and treatment options. It can be downloaded from the EULAR website: www.eular.org. Andreoli L, et al. EULAR […]
The management of lupus
Introduction Recommendations give advice to doctors and patients about the best way to treat and manage diseases. EULAR has written recommendations on the management of people with systemic lupus erythematosus (also called SLE or Lupus for short). Lupus is an autoimmune disease where the immune system attacks the body’s own tissues and causes inflammation. Lupus […]
Towards a universally accepted definition of remission in lupus
A framework for testing different definitions of remission against long-term outcomes INTRODUCTION Systemic lupus erythematosus (also known as SLE or lupus) is an autoimmune disease. It typically affects women between the ages of 15 and 50, and symptoms flare up unpredictably. Lupus is caused by complicated interactions between the immune system and environmental factors leading […]
Potential Positive Benefits of Nutritious, Well-balanced Diet in People with Lupus
Cecilia Lourdudoss, Ph.D. student at the Unit for Research Therapy, Inflammatory Diseases (ClinTRID), Karolinska Institutet in Stockholm, Sweden, spoke with the Lupus Foundation of America recently about her latest research findings on the association of diet and steroid use in people with lupus, published in Lupus Science & Medicine. In this study, vitamin D was […]
New drug tabalumab offers limited efficacy in lupus
Tabalumab will not be developed any further for lupus, but may offer insights into future trial design for other treatment options. INTRODUCTION Systemic lupus erythematosus (also known as SLE or lupus) is an autoimmune disease. It typically affects women between the ages of 15 and 50 and symptoms flare up unpredictably. Lupus is caused by […]
Long-term remission in SLE is not as rare as previously thought
Over one-third of Caucasian patients can achieve long-term remission. INTRODUCTION Systemic lupus erythematosus (also known as SLE or lupus) is an autoimmune disease. It typically affects women between the ages of 15 and 45. The cause of SLE is not known, and symptoms can vary from patient to patient. People with SLE often have severe […]
New drug atacicept may help to prevent SLE flares
High-dose atacicept prevented disease flares, although there were some safety concerns. INTRODUCTION Systemic lupus erythematosus (also known as SLE or lupus) is an autoimmune disease. It typically starts in women between the ages of 15 and 45, but can affect both genders. The cause of SLE is not known, and symptoms can vary from patient […]
