Baricitinib gives clinical improvement and inhibits joint damage in people with rheumatoid arthritis and an inadequate response or intolerance to csDMARDs INTRODUCTION Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, causing pain and disability. It is more common in older people, and affects both men and women. Baricitinib is a new […]
Category: Rheumatoid arthritis
Painful joints may predict the development of rheumatoid arthritis
Patients with clinically suspect joint pain have an increased risk of developing rheumatoid arthritis INTRODUCTION Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, causing pain and disability. It is more common in older people, but it has a high incidence in young people as well. It affects both men and women. […]
Biologics should be compared to the highest possible dose of methotrexate
Some drugs work better at higher doses. Traditionally, studies designed to show that biologic drugs are better than methotrexate have not used the highest possible dose of methotrexate to compare against. INTRODUCTION Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, causing pain and disability. It can also affect internal organs. Rheumatoid […]
Treatment-free remission may soon be a realistic goal in rheumatoid arthritis
Tapering and sometimes discontinuation of DMARDS is possible in people with rheumatoid arthritis who achieve sustained remission, hinting at the possibility that the disease could be cured. INTRODUCTION Rheumatoid arthritis is a chronic inflammatory disease that causes pain and disability. It can also affect internal organs. Rheumatoid arthritis is more common in older people, but […]
Women with rheumatoid arthritis and those treated with TNF inhibitors may be at increased risk of cervical cancer
Women with rheumatoid arthritis have a higher risk of cervical cancer, and those treated with TNF inhibitors have a further increased risk, though the link is not conclusive. INTRODUCTION Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, causing pain and disability. It can also affect internal organs. Rheumatoid arthritis is more […]
Tofacitinib effective despite previous biologic therapy
Tofacitinib is effective in reducing the signs and symptoms of rheumatoid arthritis when used either before or after biologics. INTRODUCTION Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, causing pain and disability. It can also affect internal organs. Rheumatoid arthritis is more common in older people, but there is also a […]
Can adding a musculoskeletal ultrasound assessment to an intensive early treatment strategy improve outcomes for people with rheumatoid arthritis?
Regular use of ultrasound may lead to more intensive treatment, but does not significantly affect short-term outcomes. INTRODUCTION Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints and sometimes their internal organs. Many studies have suggested that treatment and interventions should target disease in the early stages to help prevent disability and […]
Textile dust is a risk factor for the development of rheumatoid arthritis
Exposure to textile dust is associated with an increased risk of developing rheumatoid arthritis. In addition, a gene–environment interaction is also seen. INTRODUCTION Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints and sometimes their internal organs. Rheumatoid arthritis may develop for a number of reasons, and there may be a link […]
Inflammation in rheumatoid arthritis results in shortened lifespan
Much of the increase in mortality in people with rheumatoid arthritis who are also diagnosed with cancer may be due to the inflammatory effects of the arthritis or its treatment, and not the cancer. INTRODUCTION Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, causing pain and disability. It can affect both […]
Economic background can have an impact on patient-reported outcomes
There are differences in outcomes across countries, with worse physician-reported outcomes but better patient reported outcomes in low-income countries. INTRODUCTION Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, causing pain and disability. It can also affect internal organs. Rheumatoid arthritis is more common in older people, but there is also a […]
