ABP501 is similar to originator adalimumab in clinical efficacy, safety, and immunogenicity INTRODUCTION Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, causing pain and disability. It can also affect internal organs. Rheumatoid arthritis is more common in older people, but there is also a high prevalence in young adults, adolescents and […]
Category: Rheumatoid arthritis
Moderate alcohol consumption may not affect liver blood tests in people taking methotrexate
Weekly alcohol consumption of less than 14 units per week does not appear to be associated with an increased risk of abnormal liver blood tests. Introduction Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, causing pain and disability. It can also affect internal organs. Rheumatoid arthritis is more common in older […]
Sticking to a healthy diet over many years may protect against rheumatoid arthritis
Women with a healthy diet may be less likely to develop rheumatoid arthritis Introduction Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, causing pain and disability. It can also affect internal organs. Rheumatoid arthritis is more common in older people, but there is also a high prevalence in young adults, adolescents […]
No new safety signals with long-term use of tofacitinib
Side effects with tofacitinib are generally stable over time and there are no new safety signals with long-term use INTRODUCTION Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, causing pain and disability. It can also affect internal organs. Rheumatoid arthritis is more common in older people, but there is also a […]
Short-term changes on MRI predict long-term changes on X-ray
Short-term changes on MRI predict long-term changes on X-ray MRI is a valid method for monitoring joint damage in short-duration randomised clinical trials. INTRODUCTION Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, causing pain and disability. Although many treatments that stop inflammation and joint destruction have been introduced over the past […]
Filgotinib is effective in people with insufficient response to methotrexate
Filgotinib improved signs and symptoms of rheumatoid arthritis over 24 weeks and was associated with fast onset of action. INTRODUCTION Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, causing pain and disability. Filgotinib belongs to a new group of medicines called targeted synthetic disease modifying antirheumatic drugs (sometimes also called tsDMARDs). […]
Patient and doctor disagreement may reduce likelihood of remission
Differences between patient and physician evaluation of disease activity and pain may impact individual treat-to-target strategy INTRODUCTION Rheumatoid arthritis and psoriatic arthritis are two types of rheumatic disease. Both are chronic inflammatory diseases that affect a person’s joints, causing pain and disability. Rheumatoid arthritis can affect men and women of all ages. The inflammation can […]
MRI may be a valid biomarker in RA
MRI measures of inflammation and structural damage correlate independently with physical function, pain and patient global assessments INTRODUCTION Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, causing pain and disability. It is more common in older people, and affects both men and women. The use of patient-reported outcomes (often shortened to […]
Seronegative patients have higher disease activity
The 2010 ACR/EULAR classification criteria for rheumatoid arthritis may not be appropriate for people withseronegative disease INTRODUCTION Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, causing pain and disability. It can also affect internal organs. It is more common in older people, but there is also a high prevalence in youngadults, […]
RA-BUILD shows clinical improvement with baricitinib
Baricitinib gives clinical improvement and inhibits joint damage in people with rheumatoid arthritis and an inadequate response or intolerance to csDMARDs INTRODUCTION Rheumatoid arthritis is a chronic inflammatory disease that affects a person’s joints, causing pain and disability. It is more common in older people, and affects both men and women. Baricitinib is a new […]
