Authors: Victoria Shepherd, Richard Griffith, Mark Sheehan, Fiona Wood, Kerenza Hood Paper: Healthcare professionals’ understanding of the legislation governing research involving adults lacking mental capacity in England and Wales: a national survey People who lack capacity to provide informed consent are often excluded from medical research, leading to concerns that there is an evidence-bias in the […]
Category: Research Ethics
Moving Towards a New Ethical Governance Framework for Research-Clinical Hybrid Genomic Medicine
Authors: Gabrielle Samuel, Sandi Dheensa, Anneke Lucassen, Bobbie Farsides Paper: Towards a national genomics medicine service: the challenges facing clinical-research hybrid practices and the case of the 100 000 genomes project [OPEN ACCESS] The Chief Medical Officers’ 2017 report Generation Genome calls for a move towards integrated research and clinical practice in genomic medicine (i.e., research-clinical […]
Unethical World Medical Association Standards for Placebo Trials?
Guest post by Jeremy Howick Trials show that drugs called ‘interferon alpha’ extend life in people with advanced skin cancer (by a bit). If we invented a new drug to treat advanced skin cancer, most patients would want to know whether the new drug was better than interferon alpha. It would be less useful […]
Surrogacy, Obstetric Risk and the Kardashian Wests
Guest post by Nathan Hodson Kim Kardashian West and her husband Kanye West announced the birth of their third child, named Chicago, last month. Chicago West was born via surrogate. All the significant events of Kardashian West’s life have been documented season by season on Keeping Up With The Kardashians and naturally her surrogacy […]
The Real Problem With Human Head Transplantation
Guest Post: Michael S. Dauber, MA * Note: this article is being cross-posted at the Practical Ethics blog. In 2015, Sergio Canavero announced that he would perform a therapeutic head transplant procedure on a human subject by December 2017. Since then, he has recruited the assistance of surgeon Xiaoping Ren and switched from Valery Spiridonov to an […]
Ethical Issues when Modelling Brain Disorders in Non-human Primates
Guest Post: Carolyn Neuhaus, Ph.D. Paper: Ethical issues when modelling brain disorders in non-human primates In early 2016, Nature published a letter from a group of Chinese researchers reporting that they had created rhesus macaques with “autism-like” behaviours. The macaque was bred with a mutation in the MeCP2 gene. Overexpression of MeCP2 occurs in MeCP2 Duplication Syndrome, a […]
Advances in Neuroscience Strengthen Ethical Opposition to Harmful Experiments on Dogs
Guest Post: Jarrod Bailey, Cruelty Free International, London, UK. Paper: Advances in Neuroscience Imply that Harmful Experiments in Dogs are Unethical More than 200,000 dogs are used in harmful experiments every year worldwide, in research into human and animal diseases and in the testing of new drugs and agrochemicals. This continues despite significant public opposition […]
Can We Trust Research in Science and Medicine?
By Brian D. Earp (@briandavidearp) Readers of the JME Blog might be interested in this series of short videos in which I discuss some of the major ongoing problems with research ethics and publication integrity in science and medicine. How much of the published literature is trustworthy? Why is peer review such a poor quality control mechanism? How can we judge […]
Not Just About Consent: The Ethical Dimensions of Research Methodology Knowledge in IRBs
Guest Post: Sarah Wieten The recent article, “Some Social Scientists Are Tired of Asking for Permission” in the New York Times inspired a great deal of debate about the role of institutional research ethics board (IRB) oversight in social science, which some argue is in most cases unlikely to involve significant harm to participants. While […]
“NOW’s interest in pharmaceutical gender equity seems to have disappeared with its funding.”
There’s a remarkable piece on the Hastings Center’s blog by Alycia Hogenmiller about a drug called Addyi. Addyi is a drug that doesn’t work to treat a condition that doesn’t exist, pushed by campaigners who are actually industry shills. Sprout Pharmaceuticals, run by Cindy and Robert Whitehead, was determined to obtain regulatory approval for flibanserin […]