Medical research with human samples and health data—why ‘dynamic’ consent is not the solution

By Andreas Bruns and Eva C Winkler. Informed consent is a central principle of medical research ethics. Traditionally, consent is required to respect the autonomy of human research subjects—their right to make their own, informed decision about whether or not to participate in medical research. However, this principle has come under significant pressure with the […]

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Interdisciplinary collaboration to identify and address ethical issues arising from the development of irreversible, high risk medical treatments

By Alex Harris & Frederic Gilbert. There are increasing numbers of clinical trials assessing high risk, irreversible treatments.  While a clinical trial aims to assess the safety and efficacy of a clinical intervention, participants enrolled in trials of high risk, irreversible treatments may be left with significant ongoing or emerging burdens after exiting the trial. […]

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Martha’s rule: rebalancing power dynamics between patients or families and clinicians to improve patient outcomes

By Ilaria Bertini. UK media outlets have reported the upcoming implementation of Martha’s Rule within NHS foundation trusts, starting from April 2024. This rule will enable swift second medical opinions for patients, healthcare practitioners, or families who express concerns regarding the patient’s response to care provided. This new pathway takes its name from a 13-year-old […]

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Voicing the realities of patient consent to unplanned obstetric interventions

By Frances Hand*, Morganne Wilbourne*, Sophie McAllister, Louise Print-Lyons, and Meena Bhatia. Approximately 46% of primiparous women using NHS facilities undergo an obstetric intervention during their labour. For women with a planned intervention (usually a caesarean birth) conversations regarding consent are mostly straightforward and occur during the pregnancy. Where an intervention is unplanned, current practice […]

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Mindless consent

By Edwin Jesudason. How could consent be mindless, if it’s about our choosing to give permission?  We could suggest at least two ways, the first familiar, the second – and the topic of this blog – perhaps less so. The first is habitual: the mindless ‘consent’ many of us give, with a passing click or […]

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Genetic research and the collective good: participants as leaders

By Ilaria Galasso and Susi Geiger. Medical ethics has long centered around the question of how to balance the public or common good with individual rights. Different approaches to ethics would prioritize different values in the context of medical research participation. Well-established moral principles provide solid arguments both for an obligation to participate in medical […]

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