NEJM 17 Sep 2015 Vol 373 1095 Well, here’s a paper that nearly caused me to stop breathing. It was certainly followed by a sharp intake of breath. Cheyne-Stokes breathing […]
Richard Lehman’s weekly review of medical journals
Richard Lehman’s journal review—14 September 2015
NEJM 10 Sep 2015 Vol 373 997 Are any readers looking for a nice short term research project in evidence based medicine? Here you have it. On 1 September, the […]
Richard Lehman’s journal review—7 September 2015
NEJM 3 Sep 2015 Vol 373 895 The cool new look is beige and fat. Understanding beige fat may be the beginning of the end of obesity in humans. Or […]
Richard Lehman’s journal review—1 September 2015
NEJM 20-27 Aug 2015 Vol 373 726 We start with a basket trial. Say you are in a supermarket and put lots of brown things in your basket—bread, a joint […]
Richard Lehman’s journal review—27 August 2015
NEJM 6-13 Aug 2015 Vol 373 503 Outcomes in early breast cancer surgery just keep on getting better. But between 20-40% of patients who have a partial mastectomy need to […]
Richard Lehman’s journal review—3 August 2015
NEJM 30 July 2015 Vol 373 405 This week’s first paper has an interesting title: Therapeutic Hypothermia in Deceased Organ Donors and Kidney-Graft Function. It’s the first time I’ve seen […]
Richard Lehman’s journal review – 27 July 2015
NEJM 23 Jul 2015 Vol 373 307 Four summers ago I found myself dabbling in the early history of outcomes research. I was astonished to find that surgeons over a […]
Richard Lehman’s journal review—20 July 2015
NEJM 16 July 2015 Vol 373 209 I’ll say it again: “Cancer boasts the worst trials in medicine. Also the worst drug regulation. Also the worst cost/benefit ratio for new […]
Richard Lehman’s journal review—13 July 2015
NEJM 9 July 2015 Vol 373 111 First they defined a new disease category. Then they promoted a mechanistic explanation. Then they made everyone focus on the pathway that matched […]
Richard Lehman’s journal review—6 July 2015
NEJM 2 July 2015 Vol 373 11 Liraglutide for weight loss. Like the second Iraq war, we knew for years that it was coming. The propaganda was laid out well […]