“We think you may be at risk of a genetic disease”. Should direct-to-consumer genetic testing companies contact at-risk relatives?

By Philip E Baker and Jordan A Parsons. Direct-to-consumer (DTC) genetic testing is becoming increasingly popular. However, with genetic testing comes the possibility of discovering mutations that confer increased risk of genetic diseases not only to the tested individual (the proband), but also their genetic relatives. This raises the challenging ethical question of what should […]

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Close Eneph? SARS-CoV-2 challenge studies and altruistic kidney donation

By Hayden P. Nix and Charles Weijer. Human challenge studies are clinical trials in which researchers intentionally infect research participants with a pathogen. The UK government has announced plans to conduct SARS-CoV-2 challenge studies beginning in January 2021. SARS-CoV-2 human challenge studies are controversial because of the risks they pose to participants. In order to […]

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Is insisting on prospective consent in paediatric critical care research throwing the baby out with the bathwater?

By Rebecca Doyle. Robust, research evidence informs best practice and facilitates medical care that is both current and of the highest quality. In an effort to protect children and families who may be exposed to sources of vulnerability in the paediatric critical care environment, is the Australian National Statement jeopardising advancements to critical care research […]

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The current call for a (fresh) inquiry on assisted suicide

By Nataly Papadopoulou. As a society and as individuals, we face challenges in dealing with debilitating, horrible diseases causing suffering, indignity, and loss of autonomy. With increased emphasis on individual autonomy in a clinical but also in a legal setting, some patients wish to control the end of their lives. Perhaps one of the most […]

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NICE’s wrong turns: opportunity costs and missed opportunities

By Jonathan Michaels. The National Institute for Health and Care Excellence (NICE) is consulting on its methods for health technology evaluation, seeking ‘public’ views on over two thousand pages of highly technical supporting material.  NICE was established to promote “clinical and cost-effectiveness through guidance and audit” and address ‘postcode prescribing’ and has led the world […]

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Futile treatments and the Covid-19 pandemic: An underplayed ethical issue in non-ICU wards

By Francois-Xavier Goudot and Sandrine Bretonnière. It is still too early to predict how long and how many phases we are going to experience with the Covid-19 pandemic. In the wake of 2020, the rapid and massive worldwide dissemination of the virus induced physicians, ethicists and public health authorities – each at their national level […]

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