Would you enroll in this Covid-19 vaccine trial? — Ethical considerations for protecting the options of subjects in primary epidemic vaccine trials

By Arthur L. Caplan and Jerrold L. Abraham. We responded to the review in JME by Monrad about ethical issues in vaccine trials, in which the discussion was limited to secondary vaccine trials (i.e. testing additional vaccines after one or more vaccines have been approved). We are concerned that the ethics of ongoing primary vaccine […]

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PPE in the hospital: ethical decision-making that balances health professional wellbeing and duty to care

By Rosalind McDougall, Lynn Gillam, Danielle Ko, Isabella Holmes, Clare Delany Prior to the COVID-19 pandemic, clinicians in well-resourced healthcare systems usually had the information and resources they needed to appropriately protect themselves while still providing optimal care for patients.  However, achieving both staff protection and high quality patient care has now become difficult in […]

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Mechanical ventilators: the evidence of effectiveness

By Jonathan J. Darrow and Jing Luo As government leaders move to relax physical distancing requirements related to severe acute respiratory coronavirus 2 (SARS-CoV-2), a central assumption is that mechanical ventilators will form part of the safety net needed to sustain life in those afflicted with the disease it causes, Covid-19. Ventilators have been described as […]

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Must Clinical Ethics Committees involve patients or families in their meetings?

By Dominic Wilkinson @Neonatalethics and Michael Dunn @ethical_mikey Originally posted on PRACTICAL ETHICS In a high court case reported last week, a judge strongly criticised a London hospital’s clinical ethics committee (CEC). The case related to disputed treatment for a gravely ill nine-year old child. There had been a breakdown in the relationship between the […]

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Ongoing puberty suppression should be an available treatment option for non-binary adults, but case-by-case analysis is also needed

By Lauren Notini The use of medications to suppress puberty (puberty suppression or puberty blockers) in young people who identify as transgender (trans) or gender diverse (TGD) has generated ongoing debate in the media and bioethics literature. Puberty blockers are typically recommended as a treatment option for TGD young people who are experiencing gender dysphoria […]

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Utilizing parents to hand-bag ventilate when resources are scarce: Is it ethical?

By Emily E. Barsky and Sadath Sayeed Amidst the COVID-19 pandemic, many nations are coping with what resource limited settings are all too familiar with—ventilator scarcity.  In low-income countries, people— and particularly children— frequently die of reversible, acute respiratory failure due to across-the-board resource scarcity.  Some such settings have responded to this by allowing parents […]

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Toward enhanced consent for psychedelic psychiatry

By William R Smith. and Dominic Sisti. Imagine living with treatment-resistant depression. You’ve already tried several lines of medication, electroconvulsive therapy, and psychotherapy to no avail. You might have even have used augmentation strategies such as transcranial magnetic stimulation. Maybe you have spent years of your life struggling with this disease despite these attempts; maybe […]

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