Repair versus replacement for ischemic mitral regurgitation

Ischemic mitral regurgitation (MR) following myocardial infarction is common and presages a doubling in mortality for those with at least mild regurgitation.  The disorder reflects disease of the myocardium, rather than an abnormality of the valve itself. Surgical practice guidelines support intervention for severe symptomatic ischemic MR, but evidence is lacking to inform whether valvular […]

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Percutaneous Treatment of Mitral Regurgitation

Just as percutaneous therapy for coronary artery disease has revolutionized the management of patients with atherosclerosis and offered an alternative to traditional surgical management, percutaneous treatments are now becoming established for valvular heart disease.  While percutaneous aortic valves are becoming increasingly common-place, treatment options for mitral regurgitant disease remain limited. One such option in development […]

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Gender differences in the treatment of mitral valve prolapse

Mitral regurgitation (MR) may occur secondary to mitral value prolapsed (MVP), the latter having an estimated prevalence of 2.5% in the population. Severity of MR has been shown to be the main driver of outcome and also left ventricular and atrial changes, so surgical intervention remains the treatment of choice for MVP with severe MR. […]

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