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EBM Library – Systematic reviews in policymaking: part 1

  The EBM library signposts some essential reading for the practice of Evidence-Based Medicine. In this part of the library, we highlight papers that reflect the role of systematic reviews in policymaking. Kamal R. Mahtani One of the purposes of conducting systematic reviews is to provide accessible evidence to inform clinical decisions. In healthcare, they […]

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Controversies in PSA screening

  40 years after its discovery, a re-analysis of the two largest trials to date, controversially suggests PSA screening may actually be beneficial. Jack O’Sullivan Most healthcare organisations do not recommend PSA screening for prostate cancer (USPSTF, Public Health England), mainly in response to conflicting evidence about the benefits and clear evidence of harms.  PSA […]

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What can we learn from the EBM Manifesto?

  The Better Evidence for Better Healthcare Manifesto (EBM manifesto) has been launched in order to improve the implementation of evidence-based interventions by pulling together a clear set of achievable goals and a strong overview of the strategies that work best, to help deliver change better and faster. In some areas, such as the treatment of illicit […]

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What I learned from Evidence Live 2017: Fixing the “E” in EBM

On the longest (and probably hottest) day of 2017, Evidence Live kicked off at the Blavatnik School of Government, University of Oxford. Professor Carl Heneghan, new Editor-in-Chief of BMJ Evidence-Based Medicine (EBM), opened the conference with the EBM manifesto which recognizes problems in research evidence and proposes actions needed to tackle these problems. This is my summary […]

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Systematic reviews to reduce research waste

The global spend on biomedical research and development is about $250 billion, so why is so much of it still wasted, asks Kamal R. Mahtani. The global spend on biomedical research and development is estimated to be about $250 billion (£203 bn; €233 bn) each year—a not insignificant figure. In fact, it roughly equates to the amount that the UK […]

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