Richard Lehman’s journal review—19 January 2015
NEJM 15 Jan 2015 Vol 372 201 “The main challenge is to ensure better systems [of sharing data] for the future. Because ‘the optimal systematic review would have complete information […]
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Richard Lehman’s journal review—12 January 2015
NEJM 8 Jan 2015 Vol 372 113 A vaccine that works really well is the best kind of medical intervention. But a vaccine that gives partial protection is a headache. […]
Richard Lehman’s journal review—5 January 2015
JAMA 24-31 December 2014 Vol 312 2659 The effects of extreme heat on older adults: what a great topic for this cold gloomy time of the year. “Heat wave periods […]
Richard Lehman’s journal review—22 December 2014
NEJM 18 December 2014 Vol 371 2353 Try to make winter bearable by thinking of the joys of late spring, such as seeing laburnum trees in full blossom. But you […]
Richard Lehman’s journal review—15 December 2014
NEJM 11 December 2014 Vol 371 OL The clones! The clones! There is something of Edgar Allen Poe about this study, which describes how “clonal hematopoiesis with somatic mutations is […]
Richard Lehman’s journal review—8 December 2014
NEJM 4 December 2014 Vol 371 2227 “We need to remember that these drugs also have toxic effects, they are enormously and inappropriately expensive, and they haven’t cured anyone yet. […]
Richard Lehman’s journal review—1 December 2014
NEJM 27 November 2014 Vol 371 2061 Antoine Bernard-Jean Marfan (1858-1942) was a French paediatrician who lived in the happy era of medicine when you could affix your name to […]
Richard Lehman’s journal review—24 November 2014
NEJM 20 November 2014 Vol 371 1963 The melanoma trials last week got me thinking about how the current model of cancer drug research lets down trial participants and dying […]
Richard Lehman’s journal review—17 November 2014
NEJM 13 November 2014 Vol 371 1867 “Metastatic melanoma remains just over the border of curability. As we wait and hope for some breakthrough in an agonizingly incremental process, there […]
Richard Lehman’s journal review—10 November 2014
NEJM 6 November 2014 Vol 371 1771 The first paper in the New England Journal this week describes a French trial of rituximab versus azathioprine for maintenance in ANCA associated […]