Richard Lehman’s journal review—1 September 2015
NEJM 20-27 Aug 2015 Vol 373 726 We start with a basket trial. Say you are in a supermarket and put lots of brown things in your basket—bread, a joint […]
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Richard Lehman’s journal review—27 August 2015
NEJM 6-13 Aug 2015 Vol 373 503 Outcomes in early breast cancer surgery just keep on getting better. But between 20-40% of patients who have a partial mastectomy need to […]
Richard Lehman’s journal review—3 August 2015
NEJM 30 July 2015 Vol 373 405 This week’s first paper has an interesting title: Therapeutic Hypothermia in Deceased Organ Donors and Kidney-Graft Function. It’s the first time I’ve seen […]
Richard Lehman’s journal review – 27 July 2015
NEJM 23 Jul 2015 Vol 373 307 Four summers ago I found myself dabbling in the early history of outcomes research. I was astonished to find that surgeons over a […]
Richard Lehman’s journal review—20 July 2015
NEJM 16 July 2015 Vol 373 209 I’ll say it again: “Cancer boasts the worst trials in medicine. Also the worst drug regulation. Also the worst cost/benefit ratio for new […]
Richard Lehman’s journal review—13 July 2015
NEJM 9 July 2015 Vol 373 111 First they defined a new disease category. Then they promoted a mechanistic explanation. Then they made everyone focus on the pathway that matched […]
Richard Lehman’s journal review—6 July 2015
NEJM 2 July 2015 Vol 373 11 Liraglutide for weight loss. Like the second Iraq war, we knew for years that it was coming. The propaganda was laid out well […]
Richard Lehman’s journal review—29 June 2015
NEJM 25 June 2015 Vol 372 2533 The research articles in this week’s print NEJM are all about arcane stuff I’ve covered previously. The Clinical Practice article takes us back […]
Richard Lehman’s journal review—22 June 2015
NEJM 18 June 2015 Vol 372 2387 For the first time in years, I actually handled a new printed copy of the NEJM last night. What a suave production it […]
Richard Lehman’s journal review—15 June 2015
NEJM 11 June 2015 Vol 372 2307 Here at last is a study that shows some benefit from out of hospital cardiopulmonary resuscitation. It’s not a randomised trial, since that […]