Confounded

There’s a lot of confusion on confounding. We need to understand confounding when we try to use non-randomised studies to see if doing a Thing is going to produce more good than harm, or looking for risk factors we then will hope to influence to produce goodness. If we look at observational data on time-to-diagnosis […]

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More than the medicine

The end of our profession is nigh! Chatbots and AI and Hal (I’m sort of hoping that there are either very very old people, or pre-millennial film buffs reading) will take over the world! Doctors are needed no more! While this is mainly the news about diagnostic flowbots, it’s not just there we have computers […]

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When is a therapy experimental?

We’ve said before that EBM is about using the ‘best available’ evidence, and that while we’d love all our treatments to be supported by large RCTs and systematic reviews, Archimedes is living proof that this often isn’t the case. Sometimes we’ll be in the situation where the treatment could be quite reasonably subjected to a […]

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Guest Blog: 5 Tips Parents/Caregivers Can Use to Help Make Cancer Less Painful for Kids: #KidsCancerPain

Pain is one of the most distressing symptoms children living with cancer experience. It can be caused by the disease, procedures and side effects of medication. Pain can be pervasive and impact every part of a child with cancer’s life. Managing this pain has been shown to have a profound impact on a child’s health […]

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Using the power of pathology

Back in the mists of pre-clinical training, I used to believe that disease states arose through disordered bodies. That illness was a disturbance of anatomy and physiology, and that by understanding the basics of normal, we could derive the pathological, and so predict the disorder and define the therapy. Then I learned of the influence […]

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Incongruous

 I’ve struggled with spelling for most of my life and in still occasionally do pronouncing terribly wrong. (For about 4 books, I pronounced Hermione “Hermy-one” in my head, instead of “Her-my-oh-knee”, for example.) So every time I see the word ‘incongruous’ I tend to get slight shivers of spelling-test related fear. It is, however, a […]

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Spirals of re-validation

In the UK, revalidation, to the eyes of anyone in a permanent post, brings thoughts of GMC pleasing e-paperwork and the joy of yet more hours staring at a barely functional system to prove you are safe and sensible enough to not play with computers but auscultate bunnies (where necessary) and diagnose life-threatening disorders. To […]

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