GUEST POST: Is “sitting on your hands” an option these days for babies with bronchiolitis?

Paediatric doctors and nurses have long been dismayed that we have no useful interventions (other than supportive therapy) for babies with bronchiolitis. We have known for decades that using nebulisers, doing chest x-rays, and starting antibiotics are generally pointless for most infants with bronchiolitis – they are more likely to lead to overtreatment and harm […]

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Refreshing

Every now and then you’ll hit an EBM question, clinical dilemma or situation where you’ve got it at the back of your mind, or the tip of your tongue, you’ve seen something similar before. It may be a network meta-analysis, where people seem to have combined studies in a spidergram not a forest plot. A […]

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Underrepresentation

Not uncommonly, the issue of the generalisability or representativeness of a study population to the ‘real world’ is raised. There are some pretty big issues here, not least the idea that studies are undertaken in an unreal world, where troubles melt like chimney tops and sail above your lemon drops. Avoiding those sorts of mangled […]

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Endocrinology is fun!

We hope that since the takeover of the @ADC_BMJ and @ArchivesEandP accounts by our social media team, you’ve enjoyed (and learnt something from) the flurry of thematic tweeting occurring each week as much as we have had generating them. The last week @ADC_BMJ has been focussed on the subspecialty of paediatric endocrinology and diabetes, and […]

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Confounded

There’s a lot of confusion on confounding. We need to understand confounding when we try to use non-randomised studies to see if doing a Thing is going to produce more good than harm, or looking for risk factors we then will hope to influence to produce goodness. If we look at observational data on time-to-diagnosis […]

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