Refreshing

Every now and then you’ll hit an EBM question, clinical dilemma or situation where you’ve got it at the back of your mind, or the tip of your tongue, you’ve seen something similar before. It may be a network meta-analysis, where people seem to have combined studies in a spidergram not a forest plot. A […]

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Underrepresentation

Not uncommonly, the issue of the generalisability or representativeness of a study population to the ‘real world’ is raised. There are some pretty big issues here, not least the idea that studies are undertaken in an unreal world, where troubles melt like chimney tops and sail above your lemon drops. Avoiding those sorts of mangled […]

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GUEST BLOG: The R Word

By Anna Baverstock Resilience has for many become an unmentionable word. It is also a ‘trigger’ word. Often generating an intensely negative reaction in some, that then negates anything that may be discussed after. My role as Associate Director of Medical Education (ADME) with responsibility for supporting junior doctors enables me to meet with many […]

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Endocrinology is fun!

We hope that since the takeover of the @ADC_BMJ and @ArchivesEandP accounts by our social media team, you’ve enjoyed (and learnt something from) the flurry of thematic tweeting occurring each week as much as we have had generating them. The last week @ADC_BMJ has been focussed on the subspecialty of paediatric endocrinology and diabetes, and […]

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Confounded

There’s a lot of confusion on confounding. We need to understand confounding when we try to use non-randomised studies to see if doing a Thing is going to produce more good than harm, or looking for risk factors we then will hope to influence to produce goodness. If we look at observational data on time-to-diagnosis […]

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More than the medicine

The end of our profession is nigh! Chatbots and AI and Hal (I’m sort of hoping that there are either very very old people, or pre-millennial film buffs reading) will take over the world! Doctors are needed no more! While this is mainly the news about diagnostic flowbots, it’s not just there we have computers […]

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When is a therapy experimental?

We’ve said before that EBM is about using the ‘best available’ evidence, and that while we’d love all our treatments to be supported by large RCTs and systematic reviews, Archimedes is living proof that this often isn’t the case. Sometimes we’ll be in the situation where the treatment could be quite reasonably subjected to a […]

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