In pandemics, clear thinking (and explanations) matter even more

There’s been a flurry of interest about non-steroidal anti-inflammatory (NSAIDs) drugs like ibuprofen and the new coronavirus recently. The UK medicine’s safety authority have been clear that there is no good evidence of a link between severe COVID19 disease and NSAIDs, but that this isn’t a lot of evidence. When there’s not much data of […]

Read More…

Can our children’s trials work better than they do?

We’re all well aware of the problems of doing randomised clinical trials in paediatrics – small numbers, uncertainty about sample size estimates, lack of funding to undertake the studies – but are we as aware of some alternative approaches that have been used [1]? “Sequential design” studies look at comparing a series of treatments against […]

Read More…