Global patterns in ante-natal syphilis prevalence: Why is sub-Saharan Africa different?

‘Can a meaningful pattern be discerned in the large variations in syphilis rates over the last century?’ This is the question addressed by a recent systematic review – Kenyon & Tsoumanis (K&T) – based on published data on ante-natal syphilis prevalence (ASP) from those countries for which that data is available since at least 1951.   […]

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UK National Health Service (NHS) kicks PrEP into the long grass

A recent BMJ editorial condemns the NHS position that it will not consider PrEP for direct NHS funding.  The decision was first communicated in an NHS statement issued in March, then confirmed by a review on 31st May, following reconsideration in response to objections raised by interested groups.  This brought to an end an eighteen-month process […]

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Mathematical models say: switching to HPV nonavalent vaccine brings cost benefits.

STI journal issues of nearly a decade ago, when HPV vaccination was a relatively new thing, hosted a discussion on the issue of which vaccine to choose. The choice at that time, readers will remember, was between GSK’s Cervarix 2vHPV and Merck’s Gardasil 4vHPV (Morris/STIs)*.  Now, the introduction of a third alternative, Gardasil (9vHPV), seems to […]

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Is the UK meeting its national guidelines for HIV testing of MSM?

The potential role of frequent HIV testing in curbing the HIV epidemic among the MSM population has long been recognized. The introduction of the strategy of ‘opt-out’ testing in the UK (2007), as in other countries at around the same time, brought a steep rise in testing, followed by stabilization (McDaid & Hart (STIs); Saxton […]

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Can a case be made for opportunistic testing for Chlamydia?

Last month saw the publication of a revised Guidance on Chlamydia Control in Europe (2016) by the European Centre for Disease Prevention and Control.  This replaces the earlier Guidance on Chlamydia Control in Europe (2009) – though the 2016 document refers the reader to the 2009 one for more detailed descriptions of the epidemiology of […]

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Improving Partner Notification with a new online tool from SXT Health CIC – by Anatole Menon-Johansson

Improving levels of partner notification (PN) is key to reducing the transmission of STIs in the UK, but doing so has proved to be difficult, time consuming, and expensive for many. As few as 25% of sexual health care providers achieve the BASHH target of 0.6 partners seen for every patient diagnosed with an STI […]

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Another failed sub-Saharan #PrEP study: unpicking the disappointing performance of the dapivirine ring

The potential value of PrEP as an intervention in Western MSM populations has recently been conclusively demonstrated (PROUD – 86% (PROUD study/STIs/blog)), despite results from a whole series of trials in sub-Saharan African populations that seemed to cast doubt on its likely efficacy (CAPRISA 004 – 39%; iPrEX – 44%; CDC TDF2 – 62%; Partners-PrEP – 75%; FEM-PrEP – 0%; VOICE– 0%). The difference in […]

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Impressive declines in #HPV types amongst 14-24 yr olds in the US, despite poor vaccination coverage

Conclusive demonstration of cancer prevention benefits of HPV vaccination will only be possible in the relatively long term; good indicators of its probable effectiveness are, of course, already available. These include: reduced prevalence of the HPV types that have been vaccinated against; the decline in diagnoses of – or prescription for – genital warts; and […]

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Editor-in-Chief Vacancy, Sexually Transmitted Infections

Sexually Transmitted Infections (sti.bmj.com) is the world’s longest running international journal on sexual health, publishing peer reviewed original research, descriptive epidemiology, evidence-based reviews and comment on the clinical, public health, translational, sociological and laboratory aspects of sexual health from around the world. It also has an active online presence via a regular blog, podcasts, and […]

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