News and updates from www.palliativedrugs.com

Selected items from the News and Latest Additions sections of www.palliativedrugs.com, the world’s leading palliative care website with over 37,000 members from 153 Countries. Safety updates Updated advice on switching brands of anti-epileptics MHRA has updated their advice, published in 2013 (see our news item), regarding switching between different manufacturer’s products. For anti-epileptic drugs listed […]

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Effect of an Indwelling Pleural Catheter vs Talc Pleurodesis on Hospitalization Days in Patients With Malignant Pleural Effusion: The AMPLE Randomized Clinical Trial. Thomas R, Fysh ETH, Smith NA, Lee P, Kwan BCH, Yap E, Horwood FC, Piccolo F, Lam DCL, Garske LA, Shrestha R, Kosky C, Read CA, Murray K, Lee YCG. JAMA. 2017 […]

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Respiratory adverse effects of opioids for breathlessness: a systematic review and meta-analysis. Verberkt CA, van den Beuken-van Everdingen MHJ, Schols JMGA, Datla S, Dirksen CD, Johnson MJ, van Kuijk SMJ, Wouters EFM, Janssen DJA Eur Respir J. 2017 Nov 22;50(5). The effect of opioids on respiration in patients with advanced disease and chronic breathlessness was systematically […]

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Is the rationale more important than deception? A randomized controlled trial of open-label placebo analgesia. Locher C, Frey Nascimento A, Kirsch I, Kossowsky J, Meyer A, Gaab J. Pain. 2017 Dec;158(12):2320 2328. Healthy volunteers were recruited to an experimental heat pain analgesia randomized controlled trial. Forty healthy volunteers in each group were randomly assigned to […]

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News and updates from www.palliativedrugs.com

Selected items from the News and Latest Additions sections of www.palliativedrugs.com, the world’s leading palliative care website with over 30,000 members from 169 Countries. Safety updates Buccolam pre-filled syringes: medicines defect information MHRA has highlighted reports that the translucent tip-cap of Buccolam (midazolam) oromucosal syringes (all strengths) sometimes remains on the syringe tip when the […]

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News and updates from www.palliativedrugs.com

Selected items from the News and Latest Additions sections of www.palliativedrugs.com, the world’s leading palliative care website with over 30,000 members from 169 Countries. Safety updates Gabapentin: risk of severe respiratory depression The MHRA has highlighted a rare risk of severe respiratory depression in patients taking gabapentin even without concomitant opioids. Dose adjustments may be […]

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