Amyotrophic lateral sclerosis (ALS) is a rapidly progressive disorder of motor neurons in the cortex, brainstem and spinal cord, for which there is no cure. The pathophysiological mechanisms underlying ALS remain to be fully elucidated, although approximately 10% of cases were previously regarded as familial. Mutations in the superoxide dismuate-1 gene (SOD-1) were first reported […]
Latest articles
Who’s in Control Here?
According to a recently released study in Current Directions in Psychological Science, the key to self-control is practice. As in, the more you practice self-control, the more inclined you are to engage it when you need it most. Take Wednesday night for example, when two excellent hours were spent at a concert, leaping around to […]
Exercise and motor neurone disease
What advice should a neurologist provide to ALS patients about exercise?
In the midpoint of the 1938 season, it became clear there was a problem. James Kahn, a reporter who wrote often about Gehrig, wrote in one article:
“I think there is something wrong with him. Physically wrong, I mean. I don’t know what it is, but I am satisfied that it goes far beyond his ball-playing. I have seen ballplayers ‘go’ overnight, as Gehrig seems to have done. But they were simply washed up as ballplayers. It’s something deeper than that in this case, though.” […]
The Impact Commentary
The Impact Commentary, launched in the January 2012 issue, provide a modern perspective on the most highly cited JNNP papers of all time. […]
The Hospital for Incurables: what’s in a name?
By our roving blogger Dr Susanna Park Directly over the fence from my new home, there lies a complex with an impressive Victorian façade, proclaimed as the Royal Hospital for Neuro-Disability. It is clear that this facility has been operating here for a long time, probably ever since the Victorian era. What was the […]
I Never Met a Curry I Didn’t Like
For enhanced audio enjoyment click here: Handsome Devil From our roving JNNP Web Editor Clare Caldwell This month’s JNNP Featured Patient may well have been a fan of the educational philosopher Maynard Hutchins, whose most memorable quip remains, “whenever I feel the need to exercise, I lie down until it goes away.” Imagine our patient, […]
Plantar extensor, plantar flexor – does anyone care?
This week we have a post from Dr Arun Krishnan, Web Editor at JNNP: Over the last few weeks, I have been helping train and examine candidates for the specialist entry exams for the Royal Australasian College of Physicians. The candidates are fully qualified doctors with 3-4 years of hospital experience, who are planning on […]
Dopamine agonists and pathological gambling
Growing evidence suggests that dopamine agonist medications may cause pathological gambling, compulsive and impulsive shopping, compulsive eating and hypersexuality in approximately patients with Parkinsons Disease. What is going on? […]
Welcome to the JNNP Blog!
With the launch of the JNNP blog, we welcome your feedback, submissions and suggestions for future content. […]