Nonsteroidal anti-inflammatory drugs (NSAID) are frequently used as over-the-counter and prescription medications. Although prior studies have raised concern about the cardiovascular safety of these medications, detailed information on the risk of these medications in patients after myocardial infarction (MI) is lacking. In this study, retrospective Danish National Patient Registry data was evaluated for all patients […]
Tag: NSAIDs
Chronic NSAID use increases mortality from cardiovascular disease
Nonsteroidal anti-inflammatory drugs (NSAIDs) are effective and extensively used pain-killers, particularly in the treatment of chronic musculoskeletal problems. However, doubts about their safety in patients with coronary disease have surfaced, particularly since the NSAID-like COX1 inhibitor, rofecoxib, was withdrawn from the market after a demonstrated increase in cardiovascular events. Despite these concerns, compelling data on […]
NSAIDs in Chronic Heart Failure – Further Evidence of Harm
Current guidelines advise against the use of NSAIDs in patients with chronic heart failure (CHF) due to the increased risk of fluid retention. However, many NSAIDS are available over the counter (OTC), and patients obtaining them in this manner may be putting themselves at increased risk of myocardial infarction or worsening heart failure. […]