Dabigatran Unsuitable for Use with Mechanical Heart Valves

Dabigatran and other novel oral anticoagulants are effective and safe for reducing thromboembolic risk in the setting non-valvular AF.  However, it remains unclear whether these newer anticoagulants are as effective as warfarin for reducing thromboembolic complications among patients with mechanical heart valves.  As oral anticoagulation is a mainstay of therapy in patients with mechanical valves, […]

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