Richard Lehman’s journal review—3 November 2014
NEJM 30 October 2014 Vol 371 1685 The treatment of childhood and adolescent cancer is territory that most of us don’t trespass on, but we’ll need to go there this week […]
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Richard Lehman’s journal review—27 October 2014
NEJM 22 October 2014 Vol 371 1577 The whole point about tuberculosis is that it is slow. The discoverer of its causative organism, Robert Koch, called it the fungus-germ, or […]
Richard Lehman’s journal review—20 October 2014
NEJM 16 October 2014 Vol 371 1507 I hate military metaphors for cancer as much as anybody, but here is a study which describes hell in the leukaemia trenches. The […]
Richard Lehman’s journal review—13 October 2014
NEJM 9 October 2014 Vol 371 1381 With blood transfusion, it seems that less is usually better. This has been shown in renal patients and palliative care, and is now […]
Richard Lehman’s journal review—6 October 2014
NEJM 2 October 2014 Vol 371 1285 Here is a trial which had me taking my glasses off and scratching my bald patch. Why on earth should a drug company—in this […]
Richard Lehman’s journal review—29 September 2014
NEJM 25 September 2014 Vol 371 1189 This week we start with mepolizumab. Before we know it, we encounter losmapimod. Enough is enough. I think the World Health Organization should […]
Richard Lehman’s journal review—22 September 2014
NEJM 18 September 2014 Vol 371 1100 The way I have ureteric colic is so classical that just watching me sweat and groan is enough for anyone to make the […]
Richard Lehman’s journal review—15 September 2014
NEJM 11 September 2014 Vol 371 1016 Ticagrelor has had mixed fortunes since it was introduced as a new thienopyridine platelet aggregation inhibitor a few years ago. The PLATO trial […]
Richard Lehman’s journal review—8 September 2014
NEJM 4 Sep 2014 Vol 371 892 A terrific piece by Rita Redberg discusses sham controls in medical device trials. Whenever sham procedures are used in the control arms of […]
Richard Lehman’s journal review—1 September 2014
NEJM 21-28 August 2014 Vol 371 711 I have a new little grandson called Timothy. He is lucky being born in August because respiratory syncytial virus generally lies low at […]