NEJM 11 September 2014 Vol 371 1016 Ticagrelor has had mixed fortunes since it was introduced as a new thienopyridine platelet aggregation inhibitor a few years ago. The PLATO trial […]
Richard Lehman’s weekly review of medical journals
Richard Lehman’s journal review—8 September 2014
NEJM 4 Sep 2014 Vol 371 892 A terrific piece by Rita Redberg discusses sham controls in medical device trials. Whenever sham procedures are used in the control arms of […]
Richard Lehman’s journal review—1 September 2014
NEJM 21-28 August 2014 Vol 371 711 I have a new little grandson called Timothy. He is lucky being born in August because respiratory syncytial virus generally lies low at […]
Richard Lehman’s journal review—18 August 2014
NEJM 14 August 2014 Vol 371 601 The usual wisdom about sodium chloride is that the more you take, the higher your blood pressure and hence your cardiovascular risk. We’ll […]
Richard Lehman’s journal review—11 August 2014
NEJM 7 August 2014 Vol 371 497 A new gene for breast cancer susceptibility? The PALB2 gene locus has been known about for several years, but this study puts it […]
Richard Lehman’s journal review—4 August 2014
NEJM 31 July 2014 Vol 371 397 Set aside half an hour to enjoy this week’s New England Journal. The key articles are all about malaria, and they are free. […]
Richard Lehman’s journal review—28 July 2014
NEJM 24 July 2014 Vol 371 371 Long ago I had a patient who kept having odd things happen to her. She infarcted part of her cerebellum, and then did […]
Richard Lehman’s journal review—21 July 2014
NEJM 17 July 2014 Vol 371 203 Niacin is an abundant natural B vitamin, which lowers bad cholesterol and raises good cholesterol. What’s not to like? Well, niacin, unfortunately. In […]
Richard Lehman’s journal review—14 July 2014
NEJM 10 July 2014 Vol 371 107 I was very confused by this paper. It describes two trials of three drugs for premenopausal breast cancer with various permutations, and the […]
Richard Lehman’s journal review—7 July 2014
NEJM 3 July 2014 Vol 371 11 I don’t envy anyone with central lumbar spinal stenosis. The odds of benefit from surgery are slight. The pain can be there all […]