NEJM 20 November 2014 Vol 371 1963 The melanoma trials last week got me thinking about how the current model of cancer drug research lets down trial participants and dying […]
Richard Lehman’s weekly review of medical journals
Richard Lehman’s journal review—17 November 2014
NEJM 13 November 2014 Vol 371 1867 “Metastatic melanoma remains just over the border of curability. As we wait and hope for some breakthrough in an agonizingly incremental process, there […]
Richard Lehman’s journal review—10 November 2014
NEJM 6 November 2014 Vol 371 1771 The first paper in the New England Journal this week describes a French trial of rituximab versus azathioprine for maintenance in ANCA associated […]
Richard Lehman’s journal review—3 November 2014
NEJM 30 October 2014 Vol 371 1685 The treatment of childhood and adolescent cancer is territory that most of us don’t trespass on, but we’ll need to go there this week […]
Richard Lehman’s journal review—27 October 2014
NEJM 22 October 2014 Vol 371 1577 The whole point about tuberculosis is that it is slow. The discoverer of its causative organism, Robert Koch, called it the fungus-germ, or […]
Richard Lehman’s journal review—20 October 2014
NEJM 16 October 2014 Vol 371 1507 I hate military metaphors for cancer as much as anybody, but here is a study which describes hell in the leukaemia trenches. The […]
Richard Lehman’s journal review—13 October 2014
NEJM 9 October 2014 Vol 371 1381 With blood transfusion, it seems that less is usually better. This has been shown in renal patients and palliative care, and is now […]
Richard Lehman’s journal review—6 October 2014
NEJM 2 October 2014 Vol 371 1285 Here is a trial which had me taking my glasses off and scratching my bald patch. Why on earth should a drug company—in this […]
Richard Lehman’s journal review—29 September 2014
NEJM 25 September 2014 Vol 371 1189 This week we start with mepolizumab. Before we know it, we encounter losmapimod. Enough is enough. I think the World Health Organization should […]
Richard Lehman’s journal review—22 September 2014
NEJM 18 September 2014 Vol 371 1100 The way I have ureteric colic is so classical that just watching me sweat and groan is enough for anyone to make the […]