Clashing concepts

One thing I meet (fairly often) is the clash between the RCT and the patient ‘preference’. (I have to use ‘quotes’ because I know it’s the wrong phrase but I can’t find the right one.) Take an example – topical anaesthesia for accessing implanted central lines in children & young people with cancer. For those who […]

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StatsMiniBlog: Stepped Wedge Trials

You may be wondering about the phrase “Stepped Wedge Trial” (SWT) as there haven’t been many in paediatrics. (There is quite a nice one about the provision of free school breakfasts though – showed that giving free breakfast didn’t really improve attendance, or test scores, but the children didn’t feel as hungry.) They are a […]

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Sleep tight

Every so often you bump into something that you didn’t know you didn’t know. That might make a massive difference to your (or someone else’s) life. Well recently I was directed at this survival guide encouraging sleep to survive shift working and do it safely and securely. For us. The key points are: […]

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Emergency!

That was the repeated phrase of my middle child’s obsessive bedtime reading for a while. Picture of police bikes, fire engines, ambulances, mountain rescue 4×4 and lifeboats. In not one frame was the rescued individual entered into a clinical trial of therapy or diagnostics. I guess that might have been asking a bit much, but […]

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Basics: Study Type

So sometimes it’s obvious (the title says “: Randomised Controlled Trial” or “Systematic Review …”) but sometimes it’s just a bit tricky to work out what type of study you’re dealing with. The very clever folks at the AHRQ also had that – and the inconsistency of how researchers name things – and so developed […]

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Whose values?

I was reading a really fascinating article about microarray-based comparative genomic hybridisation. The authors – experts in the exploration and understanding of data that looks worrying like something from The Matrix – describe the way that such powerful genetic techniques can see what might be different about one child’s genes, and suggest groups in which the technique […]

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