Populations matter

So, as I occasionally bang on about, I spend a fair bit of time with children and young people with cancer. We do a lot of transfusions of blood components in this population, frequently because we heartlessly pour toxins into them in order to try to kill of their malignancy. We’ve been debating hard recently […]

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Basics. Size vs. bias

There’s a beautifully clear explanation behind the BMJ-EBM-journal paywall of a concept I’ve been struggling to express for some time, which is partly there in GRADE and partly grounded in common sense. Take the parachute argument — do you really need an RCT for parachutes (as there are survivors of non-‘chuted  falls) — and reductio ad […]

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#TakeoverDay 2013.

Do you know a young person who would want to blog to a worldwide group of children/young people’s clinicians? Run the twitter account of an international journal for a day? Next Friday, 22 November 2013, is the Children’s Takeover Day 2013 in the UK and we at the Archives of Diseases in Childhood, despite the fusty […]

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Debating devices

It’s really hard to persuade people that devices need evaluation like drugs do. This might be to do with the physical nature of a device: after all, if you can see the new cannula attachment, or special breathing mask, you know what it’s doing and what it must be making. Or it might be in […]

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Before, and after.

In the world of non-randomised studies there are a bucketload of variants, a common one that we see if the ‘before and after study’. This is, on the face of it, a sensible approach. Do your ‘thing’, then change stuff, do the ‘other thing’. Monitor something important you hope to change, and then if it […]

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Moving onwards

Not transition this time, but the whole focus of academia. Do we need to shift the everyday focus of research from universities producing complex lab science to every heath care provider being both an intelligent consumer and local producer of relevant research? For instance: which the following spend the greatest proportion of revenue on R&D […]

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