Single nerve conduction study in GBS: is it sufficient?

The diagnosis of GBS is a clinically based.  Nerve conduction studies are utilized to confirm the type of GBS, i.e. demyelinating versus axonal.  Serial nerve conduction studies have been proposed as a means of confirming whether an”apparently” axonal form of GBS represent distal demyelination.  Such confirmation has prognostic implications for the patients.  In addition, previous studies have suggested a limited utility of NCS in early GBS (within 10-14 days of symptom onset).  In a retrospective study, Nicolas’ group suggested that single NCS may be sufficient to establish a diagnosis of GBS, even in the early stages.  These results are interesting and somewhat contradictory  to the existing literature.


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Research paper: Electrophysiological diagnosis of Guillain–Barré syndrome subtype: could a single study suffice?

  • Yusuf A Rajabally,
  • Marie-Christine Durand,
  • James Mitchell,
  • David Orlikowski,
  • Guillaume Nicolas

J Neurol Neurosurg Psychiatry Published Online First: 9 May 2014 doi:10.1136/jnnp-2014-307815


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