The diagnosis of GBS is a clinically based. Nerve conduction studies are utilized to confirm the type of GBS, i.e. demyelinating versus axonal. Serial nerve conduction studies have been proposed as a means of confirming whether an”apparently” axonal form of GBS represent distal demyelination. Such confirmation has prognostic implications for the patients. In addition, previous studies have suggested a limited utility of NCS in early GBS (within 10-14 days of symptom onset). In a retrospective study, Nicolas’ group suggested that single NCS may be sufficient to establish a diagnosis of GBS, even in the early stages. These results are interesting and somewhat contradictory to the existing literature.
Read more at: http://jnnp.bmj.com/content/early/2014/05/09/jnnp-2014-307815.abstract
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Research paper: Electrophysiological diagnosis of Guillain–Barré syndrome subtype: could a single study suffice?
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J Neurol Neurosurg Psychiatry Published Online First: 9 May 2014 doi:10.1136/jnnp-2014-307815