Despite large reductions in blood pressure seen in early studies of renal denervation, the SYMPLICITY HTN-3 randomized trial failed to show a reduction in systolic blood pressure with renal denervation when compared to medical therapy alone. As a result, interest in renal denervation as a treatment for resistant hypertension has waned. In the DENERHTN trial, […]
Tag: renal denervation
Renal denervation misses the mark in resistant hypertension
The prospect of percutaneous renal-artery denervation to treat hypertension has been widely heralded in response to pilot studies that demonstrated marked reductions in blood pressure after renal denervation. Despite the rapid adoption of catheter-based renal artery denervation, data from large scale randomised controlled trials remains absent. A total of 535 patients with severe resistant hypertension […]