Long-term use of recommended cardiovascular (CV) risk modifying medications is low among patients at high-risk for CV events. Fixed-dose drug combination (FDC) therapy may reduce treatment gaps by lowering non-adherence, cost, complexity and therapeutic inertia. However, FDC may also reduce tailoring of individual medications and thereby lead to suboptimal risk control. The UMPIRE (Use of […]
Tag: polypill
Polypill pushes on
It has been calculated that a polypill containing asprin, a beta-blocker, a statin and an angotensin-converting enzyme inhibitor could reduce cardiovascular events in people with cardiovascular disease by about 75%. It has further been suggested that the addition of folic acid, and the use of three separate agents to lower blood pressure (each in low […]