Bioprosthetic aortic valves have played a critical role in improving both quality of life and prognosis in patients with severe aortic valve disease. Implanted either surgically (SAVR) or percutaneously (TAVI), they provide restoration of valve function without the need for anticoagulation as required with mechanical valves. This study was the result of clinical evaluation of […]
Category: Valvular Disorders
Long-Term Outcomes of Transcatheter Aortic Valve Replacement
The Placement of Aortic Transcatheter Valves (PARTNER) trial demonstrated that transcatheter aortic valve replacement (TAVR) for high-risk patients with aortic stenosis resulted in similar outcomes at 1, 2 and 3 years compared with surgical aortic valve replacement (SAVR). The present study reports the 5-year outcomes of this trial. The study enrolled 699 patients who were […]
Clinical Outcomes at 1 Year Following Transcatheter Aortic Valve Replacement
To date, long-term outcome data following transcatheter aortic valve replacement (TAVR) has only been available from clinical trial data. Evaluating long-term outcomes of TAVR in real-world use is important to ensure the anticipated benefits are observed in routine clinical practice. Using data from the Society of Thoracic Surgeons/American College of Cardiology (STS/ACC) Transcatheter Valve therapies […]
Surgical Repair of Moderate Mitral Regurgitation at the Time of CABG Lacks Clear Benefit
Ischemic mitral regurgitation (MR) is common and associated with poor outcomes among patients undergoing bypass surgery. However, it remains unknown whether repair of ischemic MR concurrent to CABG leads to better patient outcomes. To address this important clinical question, this multi-center study randomly assigned 301 patients with moderate ischemic MR to CABG alone or CABG […]
Long-term outcomes of mechanical versus bioprosthetic aortic valve replacement in younger adults
Younger adults requiring aortic valve replacement often receive a mechanical valve given concerns over durability of bioprosthetic valves. However, prior studies have been underpowered to compare long-term survival implications of mechanical versus bioprosthetic valve replacement in younger adults. In this retrospective cohort from the New York Statewide Planning and Research Cooperative System (SPARCS) , 4253 […]