Spontaneous resolution of any malignancy is a cause for documentation and celebration every time it happens particularly for its rarity of occurrence.

Gladwish, Clarke and Bezjak have done it commendably as well as raised the intriguing question as to why this happens ( or doesn’t more often).They have looked at multiple mechanisms that may have led to this possibility ranging from psycho-neuro-immunological to hormonal or herbal but as expected all mechanisms appeared inadequate in describing a miraculous outcome in this 81 year old who continues to do well on follow up.

Rakesh Biswas
Deputy Editor

Spontaneous regression in advanced non-small cell lung cancer