Q: Clear CSF – Does it exclude meningitis?

Many attempts at LPA 20 month old presented with 1-day history of temperature, off food and ‘not herself’. Clinical examination showed a slightly irritable child with temperature 38.80C, slightly congested throat and doubtful neck stiffness. An LP shows WCC 2, RCC 0. A diagnosis of viral illness is made, and antibiotics are not commenced.

Brave? Stupid? Evidence based? Drs Ray & Rylance from Newcastle give us this provocative scenario.

Can a relatively normal CSF – indeed can a completely white-cell free CSF – be relied on to rule out menigitis?

And if it can’t, do we need to change how we practice?


Photo from http://flickr.com/photos/26837176@N00/481711124/ under creativecommons 2.0

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