Is treatment for HIV a potential cure for multiple sclerosis?

HIV and multiple sclerosis (MS) are chronic conditions that, despite a massive amount of research, remain essentially incurable. The marked progress in treatment for these conditions has meant that both are now treatable, with the goal of treatment focussing on maintaining independence and quality of life. In the case of HIV, ensuring prolonged survival is […]

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Cervical sensory axonal dysfunction in radiculopathy: A novel concept!

Cervical radiculopathy is a common issue for neurologists. While motor dysfunction has been traditionally assessing using needle EMG techniques, thereby confirming the diagnosis, frequently only sensory symptoms may be evident. In such cases, the diagnostic time may be protracted. In an upcoming issue of JNNP (ON-LINE FIRST) Lin and colleagues tackle this issue in a […]

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Lamotrigine safer in pregnancy after all!

The risk of fetal malformations is a considerable therapeutic consideration in pregnant patients that suffer epilepsy.  the need to control seizures effectively is counterbalanced by toxicity of medications.  While lamotrigine was considered as a safer option than other anti-epiletics, doubt was cast upon this assertion.  In this issue of JNNP, an important study conducted by […]

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Is FOSMN syndrome a form of ALS?

Facial onset sensory and  motor neuronopathy (FOSMN syndrome) is a rare neurodegnerative disorder of unknown etiology.  Clinically it may resemble ALS, albeit only in the motor component.  The marked sensory abnormalities, which dominate the phenotype in the early stages of the disease process, and the prolonged survival, clearly argue against an ALS phenotype.  In this […]

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Sudden changes in cognition in MS: the isolated cognitive relapse.

Of all the types of functional difficulties that a patient with multiple sclerosis (MS) can experience, cognitive change remains the area that is hardest to delineate. MS patients may experience changes in memory, attention, reasoning and executive function that can be subtle and therefore hard to detect clinically, but significant enough to compromise their daily […]

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