Cardiac biomarkers and prognosis in COPD

Cardiovascular disease is common in patients with COPD with the two conditions often being linked by the common aetiology of smoking.  Moreover, dysfunction in one organ system can transmit to the other with severe hypoxemia, pulmonary hypertension, and systemic inflammation all potentially impacting on cardiac function.  However, the interplay between lung and cardiac disease is […]

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Anticholinergics increase risk of cardiovascular death

Inhaled anticholinergics – such as ipratropium or tiotropium bromide – are commonly prescribed to patients with chronic obstructive pulmonary disease (COPD).  A previous analysis of 19 short-term placebo-controlled trials had suggested a possible increased risk of stroke with inhaled tiotropium, therefore Singh et al. performed a meta-analysis of 17 trials enrolling 14783 patients in order […]

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