Cluster-randomised non-inferiority trial comparing DVD-assisted and traditional genetic counselling in systematic population testing for BRCA1/2 mutations

Newer genetic counselling approaches are needed to test large populations for cancer gene alterations. We compared traditional face-to-face counselling with a DVD assisted approach. This randomised study was undertaken in the London Jewish population while testing for BRCA gene alterations. We found DVD assisted counselling was not inferior to traditional face-to-face counselling for increase in knowledge and counselling satisfaction. Compared to traditional counselling it led to an equivalent number of people undergoing genetic-testing and cost savings of £14/person counselled. 98% people found the DVD length & information satisfactory, 85%-89% felt it improved their understanding and 95% would recommend it to others. (By Dr. Ranjit Manchanda, )

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