TB: Pseudodementia due to intracranial tuberculomas

This report summarises a case history of a 25-year-old woman with a well known complication of tuberculosis, intracranial tuberculoma, manifest clinically with a depressed conscious level and cognitive slowness (“pseudodementia”) a few months after the initiation of anti-TB therapy. CT scan showed several tuberculoma with surrounding oedema. After re-institution of prednisolone the symptoms subside. The learning points, as stated by the authors, are that tuberculoma need not present with focal neurological sequelae and that reversible causes for declining cognitive function should be carefully sought and corrected.

Reviewer
Kirsten Moller

Pseudodementia due to intracranial tuberculomas: an unusual presentation