News and updates from www.palliativedrugs.com

Selected items from the News and Latest Additions sections of www.palliativedrugs.com, the world’s leading palliative care website.   Safety updates Codeine restricted use in children The MHRA have restricted the use of codeine in children following the results of a European safety review (see our news item 16-10-2012). Codeine is now contraindicated in: all children […]

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Shortcuts August 2013   Support Care Cancer. 2013 Sep;21(9):2599-607 Testosterone replacement for fatigue in hypogonadal ambulatory males with advanced cancer: a preliminary double-blind placebo-controlled trial Del Fabbro E, Garcia JM, Dev R, Hui D, Williams J, Engineer D, Palmer JL, Schover L, Bruera E. In this randomized, double-blinded placebo-controlled trial the effect of testosterone replacement on […]

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Shortcuts June 2013   Clin J Pain. 2013 Mar 26. [Epub ahead of print] Do Patient-perceived Pros and Cons of Opioids Predict Sustained Higher-Dose Use? Thielke SM, Turner JA, Shortreed SM, Saunders K, Leresche L, Campbell CI, Weisner CC, Korff MV. Using a patient completed questionnaire, this study evaluated the effect of opioids (≥50 mg […]

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News and updates from www.palliativedrugs.com

Selected items from the News and Latest Additions sections of www.palliativedrugs.com, the world’s leading palliative care website. Safety updates Thalidomide: increased risk of haematological second primary malignancies The MHRA has highlighted the risk of haematological second primary malignancies (acute myeloid leukaemia and myelodysplastic syndromes) when treating patients with thalidomide. The data was from an ongoing study […]

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News and updates from www.palliativedrugs.com

Selected items from the News and Latest Additions sections of www.palliativedrugs.com, the world’s leading palliative care website. Safety updates MHRA infusion device warning with 50mL syringes The UK Medicines and Healthcare products Regulatory Agency (MHRA) has issued two separate warnings of the risk of false occlusion alarms occurring with certain 50mL syringes: 50mL Luer Lok Plastipak […]

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Shortcuts May 2013   J Pain. 2013 Feb 26. [Epub ahead of print] Lack of Correlation Between Opioid Dose Adjustment and Pain Score Change in a Group of Chronic Pain Patients. Chen L, Vo T, Seefeld L, Malarick C, Houghton M, Ahmed S, Zhang Y, Cohen A, Retamozo C, St Hilaire K, Zhang V, Mao […]

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News and updates from www.palliativedrugs.com

Selected items from the News and Latest Additions sections of www.palliativedrugs.com, the world’s leading palliative care website.   Hot topics NICE changes its name The National Institute for Health and Clinical Excellence (NICE), has changed its name and is now known as the National Institute for Health and Care Excellence, still retaining the acronym NICE. […]

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News and updates from www.palliativedrugs.com

Selected items from the News and Latest Additions sections of www.palliativedrugs.com, the world’s leading palliative care website.   Hot topics   Free access to the on-line Palliative Care Formulary in Scotland From April 2013, NHS Education for Scotland has subscribed to the on-line Palliative Care Formulary (PCF4+). The content is continually updated and represents the […]

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The Effect of Opioid Therapy on Endocrine Function. Brennan MJ. This review summarises the major effects of opioids on the endocrine system, outlining the long-term effects of their use, which can include reduced libido and sexual function, infertility, mood disorders and bone demineralisation. Although the effects of opioids on the endocrine system are relatively common […]

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