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Effects of smoking and body mass index on the exposure of fentanyl in patients with cancer. Kuip EJM, Oldenmenger WH, Thijs-Visser MF, de Bruijn P, Oosten AW, Oomen-de Hoop E, Koolen SLW, Van der Rijt CCD, Mathijssen RHJ. PLoS One. 2018 Jun 8;13(6):e0198289 A prospective single-centre pharmacokinetic study examined the effect of smoking and body […]

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Cognitive Impairment and Pain Among Nursing Home Residents With Cancer. Dubé CE, Mack DS, Hunnicutt JN, Lapane KL. J Pain Symptom Manage. 2018 Jun;55(6):1509-1518.   A cross-sectional study in the US looked at the variation of the documentation and management of pain in cancer patients with cognitive impairment who were newly admitted to residential homes […]

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The effects of multi-disciplinary psycho-social care on socio-economic problems in cancer patients: a cluster-randomized trial. Singer S, Roick J, Meixensberger J, Schiefke F, Briest S, Dietz A, Papsdorf K, Mössner J, Berg T, Stolzenburg JU, Niederwieser D, Keller A, Kersting A, Danker H Support Care Cancer. 2018 Jun;26(6):1851-1859 A powered cluster-randomized trial of 13 hospital […]

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The impact of therapeutic opioid agonists on driving-related psychomotor skills assessed by a driving simulator or an on-road driving task: A systematic review. Ferreira DH, Boland JW, Phillips JL, Lam L, Currow DC Palliat Med. 2018 Apr;32(4):786-803 This is a systematic review to assess the effect of opioids on driving safety in patients with chronic […]

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From will to live to will to die: oncologists, nurses, and social workers identification of suicidality in cancer patients. Granek L, Nakash O, Ariad S, Chen W, Birenstock-Cohen S, Shapira S, Ben-David M Support Care Cancer. 2017 Dec;25(12):3691-3702 A qualitative study in Israel, interviewed 20 nurses, 23 oncologists and 18 social workers and used grounded […]

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Effect of an Indwelling Pleural Catheter vs Talc Pleurodesis on Hospitalization Days in Patients With Malignant Pleural Effusion: The AMPLE Randomized Clinical Trial. Thomas R, Fysh ETH, Smith NA, Lee P, Kwan BCH, Yap E, Horwood FC, Piccolo F, Lam DCL, Garske LA, Shrestha R, Kosky C, Read CA, Murray K, Lee YCG. JAMA. 2017 […]

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Respiratory adverse effects of opioids for breathlessness: a systematic review and meta-analysis. Verberkt CA, van den Beuken-van Everdingen MHJ, Schols JMGA, Datla S, Dirksen CD, Johnson MJ, van Kuijk SMJ, Wouters EFM, Janssen DJA Eur Respir J. 2017 Nov 22;50(5). The effect of opioids on respiration in patients with advanced disease and chronic breathlessness was systematically […]

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Is the rationale more important than deception? A randomized controlled trial of open-label placebo analgesia. Locher C, Frey Nascimento A, Kirsch I, Kossowsky J, Meyer A, Gaab J. Pain. 2017 Dec;158(12):2320 2328. Healthy volunteers were recruited to an experimental heat pain analgesia randomized controlled trial. Forty healthy volunteers in each group were randomly assigned to […]

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C-reactive protein, symptoms and activity of daily living in patients with advanced cancer receiving palliative care. Amano K, Maeda I, Morita T, et al J Cachexia Sarcopenia Muscle. 2017 Jun;8(3):457-465. A secondary data analysis of a cross-sectional study looked at the associations between C-reactive protein (CRP) level, manual muscle testing of limbs, symptoms and activities […]

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